LAYERED NON-FOULING, ANTIMICROBIAL ANTITHROMBOGENIC COATINGS
First Claim
1. A composition comprising a functionalized substrate having covalently bound thereto a non-fouling polymeric top coat,
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Accused Products
Abstract
Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material
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Citations
38 Claims
- 1. A composition comprising a functionalized substrate having covalently bound thereto a non-fouling polymeric top coat,
Specification