DEVICE SYSTEM AND METHOD FOR MONITORING AND CONTROLLING BLOOD ANALYTE LEVELS

• US 20100145317A1
• Filed: 04/09/2008
• Published: 06/10/2010
• Est. Priority Date: 04/19/2007
• Status: Abandoned Application

• Current Assignee: C.G.M.3, Ltd.
• Original Assignee: C.G.M.3, Ltd.
• Inventors: Phillip, Moshe, Laster, Morris
• Application Number:
  US12/450,919
• Publication Number:
  US 20100145317A1
• Time in Patent Office: Days
• US Class Current: 604/891.100
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/417 the bone marrow
• CPC Class Codes: A61B 5/4504 Bones A61B5/4547 takes precedence
• CPC Class Codes: A61B 5/6864 Burr holes

Abstract

A device and system for monitoring an analyte in a subject and for controlling blood analyte levels are provided. The device and system include a sensor element which is designed and configured for detecting the analyte in blood flowing through the bone of the subject.

Claims

1-36. -36. (canceled)

37. A device for monitoring an analyte in a subject comprising a sensor element being designed and configured for detecting the analyte in blood flowing through a bone of the subject.

38. The device of claim 37, wherein the device is completely implanted within tissue of the subject.

39. The device of claim 38, wherein said sensor element is implanted within bone tissue and is designed and configured for contacting blood flowing within a blood sinus of said bone tissue.

40. The device of claim 37, wherein said sensor element is anchored to bone tissue.

41. The device of claim 37, further comprising a wireless communication unit for remotely communicating with a wireless control unit.

42. The device of claim 37, further comprising circuitry for remotely powering said sensor element.

43. The device of claim 37, wherein said analyte is glucose.

44. A system for monitoring an analyte in a subject comprising a device including a sensor element being designed and configured for detecting the analyte in blood flowing through a bone of the subject and a reservoir for providing at least one composition capable of modifying a level of the analyte in said blood flowing through said bone of the subject.

45. The system of claim 44, wherein said sensor element is implanted within bone tissue and is designed and configured for contacting blood flowing within a blood sinus of said bone tissue.

46. The system of claim 44, further comprising a wireless control unit for wirelessly controlling said device

47. The system of claim 44, wherein said analyte is glucose.

48. The system of claim 46, wherein said wireless control unit is capable of closed loop operation.

49. The system of claim 44, further comprising a mechanism for pumping said composition from said reservoir to said blood flowing through said bone.

50. The system of claim 44, wherein said reservoir further includes a filling port.

51. The system of claim 44, wherein said at least one composition is insulin or glucagon.

52. A method of controlling a blood glucose level in a subject in need comprising determining a glucose level of the subject in need in blood flowing through bone tissue and if needed, administering an appropriate amount of insulin or glucagon to the subject in need to control the blood glucose level.

53. The method of claim 52, wherein said determining said glucose level is effected via a glucose sensor implanted within bone tissue of the subject.

54. The method of claim 52, wherein said bone is an iliac crest bone.

55. The method of claim 52, wherein said administering an appropriate amount of insulin is effected via an insulin containing reservoir implanted in tissue of the subject in need.

56. The method of claim 52, wherein said administering is effected automatically under closed loop control.