IN-LINE TREATMENT OF YARN PRIOR TO CREATING A FABRIC

• US 20100151114A1
• Filed: 12/17/2009
• Published: 06/17/2010
• Est. Priority Date: 12/17/2008
• Status: Abandoned Application

• Current Assignee: Zimmer Incorporated (Zimmer Biomet Holdings, Inc.)
• Original Assignee: Zimmer Incorporated (Zimmer Biomet Holdings, Inc.)
• Inventors: Parrott, Russell M.
• Application Number:
  US12/640,655
• Publication Number:
  US 20100151114A1
• Time in Patent Office: Days
• US Class Current: 427/2.260
• CPC Class Codes: A61F 2/30756 Cartilage endoprostheses A61F2/3603 takes precedence
• CPC Class Codes: A61F 2002/0086 for preferentially controlling or promoting the growth of specific types of cells or tissues of bone tissue onto implantable joints A61F2002/3093
• CPC Class Codes: A61F 2002/009 for hindering or preventing attachment of biological tissue of bone tissue onto implantable joints A61F2002/30932
• CPC Class Codes: A61F 2002/30028 differing in tissue ingrowth capacity, e.g. made from both ingrowth-promoting and ingrowth-preventing parts
• CPC Class Codes: A61F 2002/30031 differing in wettability, e.g. in hydrophilic or hydrophobic behaviours
• CPC Class Codes: A61F 2002/30766 Scaffolds for cartilage ingrowth and regeneration
• CPC Class Codes: A61F 2002/3093 for promoting ingrowth of bone tissue
• CPC Class Codes: A61F 2002/30932 for retarding or preventing ingrowth of bone tissue
• CPC Class Codes: A61F 2002/30971 Laminates, i.e. layered products
• CPC Class Codes: A61F 2002/4495 having a fabric structure, e.g. made from wires or fibres
• CPC Class Codes: A61F 2250/0051 differing in tissue ingrowth capacity, e.g. made from both ingrowth-promoting and ingrowth-preventing parts
• CPC Class Codes: A61F 2250/0056 differing in wettability, e.g. in hydrophilic or hydrophobic behaviours
• CPC Class Codes: A61F 2310/00011 Metals or alloys
• CPC Class Codes: A61F 2310/00161 Carbon; Graphite
• CPC Class Codes: A61F 2310/00179 Ceramics or ceramic-like structures
• CPC Class Codes: A61F 2310/00329 Glasses, e.g. bioglass
• CPC Class Codes: A61F 2310/00365 Proteins; Polypeptides; Degradation products thereof
• CPC Class Codes: D06M 10/025 Corona discharge or low temperature plasma
• CPC Class Codes: D06M 10/08 Organic compounds

Abstract

A woven orthopedic implant for cartilage replacement having layered functionality and a method of forming the same. The woven orthopedic implant may include bottom layer of fibers that promotes anchoring to bone, and intermediate layer of fibers that promotes soft tissue attachment, and a top layer of fibers that promotes lubrication. The method may involve treating the surfaces of fibers before weaving the fibers together.

Claims

1. A method of forming an orthopedic implant for cartilage replacement from a first plurality of fibers and a second plurality of fibers, each of the first and second plurality of fibers having a surface, the method comprising the steps of:

treating the surfaces of the first plurality of fibers to make the first plurality of fibers more hydrophilic than the second plurality of fibers; and

after the treating step, weaving together the first plurality of fibers to form a top layer of the orthopedic implant and weaving together the second plurality of fibers to form a bottom layer of the orthopedic implant that is coupled to the top layer of the orthopedic implant, the top layer defining an articulating surface of the orthopedic implant and the bottom layer defining a bone-contacting surface of the orthopedic implant.

2. The method of claim 1, wherein the treating step comprises adding one of a hydroxyl functional group and a carboxyl functional group to the surfaces of the first plurality of fibers.

3. The method of claim 1, wherein the treating step comprises increasing the polarity of the surfaces of the first plurality of fibers.

4. The method of claim 1, further comprising the step of treating the surfaces of the second plurality of fibers before the weaving step to alter the surfaces of the second plurality of fibers.

5. The method of claim 4, wherein treating the surfaces of the second plurality of fibers comprises increasing the hydrophobicity of the second plurality of fibers.

6. The method of claim 4, wherein treating the surfaces of the second plurality of fibers comprises roughening the surfaces of the second plurality of fibers.

7. The method of claim 4, wherein treating the surfaces of the second plurality of fibers comprises bonding one of a protein and a peptide to the surfaces of the second plurality of fibers.

8. The method of claim 7, wherein the peptide comprises arginine-glycine-aspartate.

9. The method of claim 1, further comprising the steps of:

providing a third plurality of fibers; and

weaving together the third plurality of fibers to form an intermediate layer of the orthopedic implant located between the top and bottom layers, the third plurality of fibers being more hydrophobic than the first plurality of fibers and more hydrophilic than the second plurality of fibers.

10. The method of claim 1, wherein both the first and second plurality of fibers comprise ultra-high molecular weight polyethylene.

11. A method of forming an orthopedic implant for implantation into a cartilage defect site of a patient'"'"'s body, the cartilage defect site being surrounded by remaining bone and remaining cartilage, the method comprising the steps of:

providing a first plurality of fibers and a second plurality of fibers, each of the first and second plurality of fibers having a surface;

treating the surfaces of the first plurality of fibers to increase the hydrophilicity of the first plurality of fibers;

after the treating step, weaving together the first plurality of fibers to form a top layer of the orthopedic implant and weaving together the second plurality of fibers to form a bottom layer of the orthopedic implant that is coupled to the top layer of the orthopedic implant, the orthopedic implant sized for implantation into the cartilage defect site with the bottom layer of the orthopedic implant positioned adjacent to the remaining bone and the top layer of the orthopedic implant positioned adjacent to the remaining cartilage.

12. The method of claim 11, wherein the treating step comprises adding one of a hydroxyl functional group and a carboxyl functional group to the surfaces of the first plurality of fibers.

13. The method of claim 11, further comprising the step of treating the surfaces of the second plurality of fibers before the weaving step to alter the surfaces of the second plurality of fibers, the treated surfaces of the second plurality of fibers differing from the treated surfaces of the first plurality of fibers.

14. The method of claim 13, wherein the step of treating the surfaces of the second plurality of fibers comprises making the surfaces of the second plurality of fibers more hydrophobic in nature.

15. The method of claim 13, wherein the step of treating the surfaces of the second plurality of fibers comprises roughening the surfaces of the second plurality of fibers.

16. The method of claim 13, wherein the step of treating the surfaces of the second plurality of fibers comprises bonding one of a protein and a peptide to the surfaces of the second plurality of fibers.

17. The method of claim 11, further comprising the steps of:

providing a third plurality of fibers; and

weaving together the third plurality of fibers to form an intermediate layer of the orthopedic implant located between the top and bottom layers, the third plurality of fibers being more hydrophobic than the first plurality of fibers and more hydrophilic than the second plurality of fibers.

18. A woven orthopedic implant for cartilage replacement having an articulating surface and a bone-contacting surface opposite the articulating surface, the orthopedic implant comprising:

a first plurality of fibers interwoven to form a top layer of the orthopedic implant, the top layer defining the articulating surface of the orthopedic implant, each of the first plurality of fibers having an exterior surface that is treated to promote articulation;

a second plurality of fibers interwoven to form a bottom layer of the orthopedic implant, the bottom layer defining the bone-contacting surface of the orthopedic implant, each of the second plurality of fibers having an exterior surface that promotes bone attachment; and

a third plurality of fibers interwoven to form an intermediate layer of the orthopedic implant coupled to both the top and bottom layers of the orthopedic implant, each of the third plurality of fibers having an exterior surface that promotes soft tissue attachment.

19. The orthopedic implant of claim 18, wherein the treated exterior surfaces of the first plurality of fibers are more hydrophilic than exterior surfaces of the second plurality of fibers.

20. The orthopedic implant of claim 18, wherein the treated exterior surfaces of the first plurality of fibers include one of a hydroxyl functional group and a carboxyl functional group bonded to the treated exterior surfaces.

21. The orthopedic implant of claim 18, wherein the second plurality of fibers are more rigid than the first plurality of fibers.

22. The orthopedic implant of claim 18, wherein both the first and second plurality of fibers comprise ultra-high molecular weight polyethylene.