Implantable Medical Devices Having Multiblock Copolymers
First Claim
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1. An implantable medical device comprising:
- a biodegradable multiblock copolymer comprising at least three blocks;
wherein said at least three blocks includes at least one inner block and two end blocks;
further wherein each of said at least one inner block comprises monomers selected from the group consisting of e-caprolactone, r-butylactone, trimethylene carbonate, caprolactone derivatives, P-Dioxanone, and combinations thereof; and
further wherein each of said end blocks comprises monomers selected from the group consisting of l-lactide, D-lactide, glycolide, and L,D-lactide, and combinations thereof.
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Abstract
Provided herein are implantable medical devices comprising a biodegradable multiblock copolymer comprising at least three blocks; wherein the at least three blocks includes at least one inner block and two end blocks; further wherein each of the at least one inner block comprises monomers selected from the group consisting of e-caprolactone, r-butylactone, trimethylene carbonate, caprolactone derivatives, P-Dioxanone, and combinations thereof; and further wherein each of the end blocks comprises monomers selected from the group consisting of l-lactide, D-lactide, glycolide, L,D-lactide, and combinations thereof.
22 Citations
20 Claims
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1. An implantable medical device comprising:
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a biodegradable multiblock copolymer comprising at least three blocks; wherein said at least three blocks includes at least one inner block and two end blocks; further wherein each of said at least one inner block comprises monomers selected from the group consisting of e-caprolactone, r-butylactone, trimethylene carbonate, caprolactone derivatives, P-Dioxanone, and combinations thereof; and further wherein each of said end blocks comprises monomers selected from the group consisting of l-lactide, D-lactide, glycolide, and L,D-lactide, and combinations thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A self-expanding vascular stent consisting essentially of:
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a biodegradable triblock copolymer consisting essentially of a poly(trimethylene carbonate) center block and two poly(L-lactide-co-glycolide) end blocks. - View Dependent Claims (20)
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Specification