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DYNAMIC AUTOFOCUS METHOD AND SYSTEM FOR ASSAY IMAGER

  • US 20100157086A1
  • Filed: 12/15/2009
  • Published: 06/24/2010
  • Est. Priority Date: 12/15/2008
  • Status: Abandoned Application
First Claim
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1. A method for controlling focus dynamically of a sample imager, comprising:

  • scanning a sample with an optical assembly by apportioning the sample into a plurality of regions defined by a scan pattern, the optical assembly having a focal setting with respect to the sample, thereby obtaining images of the plurality of regions;

    shifting the focal setting of the optical assembly during scanning of the sample, whereby the images have an associated degree of focus corresponding to the focal setting of the optical assembly;

    analyzing the images to obtain at least two focus scores, the focus scores representing a degree to which the optical assembly was in focus when detecting the images; and

    adjusting the focus setting based on a function of the at least two focus scores.

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