TUNABLE ELASTOMERIC NANOCHANNELS FOR NANOFLUIDIC MANIPULATION
First Claim
Patent Images
1. A microfluidic system, comprising:
- a) a substrate comprising at least one inlet and at least one outlet formed in said substrate, wherein said inlet and outlet are in fluid communication with one or more elastomeric nanochannels formed in said substrate; and
b) a component configured to exert strain on said nanochannels.
3 Assignments
0 Petitions
Accused Products
Abstract
The invention relates to tunable elastomeric nanochannels for nanofluidic manipulation. In particular, the present invention relates to nanochannels for performing biological assays.
-
Citations
27 Claims
-
1. A microfluidic system, comprising:
-
a) a substrate comprising at least one inlet and at least one outlet formed in said substrate, wherein said inlet and outlet are in fluid communication with one or more elastomeric nanochannels formed in said substrate; and b) a component configured to exert strain on said nanochannels. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
-
16. A method, comprising:
contacting a biological molecule with a substrate comprising at least one inlet and at least one outlet formed in said substrate, wherein said inlet and outlet are in fluid communication with one or more elastomeric nanochannels formed in said substrate under conditions such that said biological molecule enters said nanochannels. - View Dependent Claims (17, 18, 19, 20, 21)
-
22. A cell growth system, comprising:
-
a) a substrate comprising at least one inlet and at least one outlet formed in said substrate, wherein said inlet and outlet are in fluid communication with one or more elastomeric nanochannels formed in said substrate; b) a component configured to exert strain on said nanochannels such that the cross section of said nanochannels are altered; and c) a plurality of cells or cellular portions contained within said nanochannels.
-
-
23. A method for fabrication of a nanochannel, comprising:
- stretching a substrate comprising at least one stiff thin film sandwiched by one or more compliant materials under conditions such that at least one elastomeric nanaochannel is generated.
- View Dependent Claims (24, 25, 26, 27)
Specification