DEVICE AND METHOD FOR DETERMINING ANALYTE LEVELS
First Claim
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1. An implantable device for measuring an analyte, the device comprising:
- a sensor body comprising a sensor interface configured to measure an analyte;
an angiogenic layer disposed on at least a portion of the sensor interface; and
an anchoring material attached to the sensor body and configured for anchoring the sensor body to a host tissue,wherein the angiogenic layer comprises a micro-geometry configured to create a new capillary bed in close proximity to the sensor interface.
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Abstract
Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
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Citations
22 Claims
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1. An implantable device for measuring an analyte, the device comprising:
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a sensor body comprising a sensor interface configured to measure an analyte; an angiogenic layer disposed on at least a portion of the sensor interface; and an anchoring material attached to the sensor body and configured for anchoring the sensor body to a host tissue, wherein the angiogenic layer comprises a micro-geometry configured to create a new capillary bed in close proximity to the sensor interface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. An implantable device for measuring an analyte, the device comprising:
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a sensor body comprising a sensor configured to measure an analyte; and a composite bilayer membrane comprising an angiogenic layer and a bioprotective membrane disposed on at least a portion of the sensor. - View Dependent Claims (16, 17, 18, 19, 20)
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21. An implantable device for measuring an analyte in a biological fluid, the device comprising:
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a sensor body comprising a sensor interface; an angiogenic layer disposed on at least a portion of the sensor interface; and a material for anchoring the sensor body to a host tissue, wherein the implantable device comprises porous silicone. - View Dependent Claims (22)
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Specification