System and Method for Determining Volume-Related Parameters of Ocular and Other Biological Tissues
First Claim
1. A system for determining volume-related parameters of a biological tissue, comprising:
- a light source for projecting light towards the biological tissue;
a receiver for receiving light reflected from the biological tissue at two spectral wavelengths;
an image acquisition system in communication with the receiver for forming an image from the reflected light at each wavelength; and
a processor for applying a mathematical model to the image which compares the absorption of light by the biological tissue at a selected image point at each of the two spectral wavelengths to determine the volume-related parameters of the biological tissue at that location.
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Abstract
A system and method for determining volume-related parameters of a biological tissue, such as ocular tissue, include a light source for projecting light towards the biological tissue, a receiver for receiving light reflected from the biological tissue at two spectral wavelengths, and an image acquisition system in communication with the receiver for forming an image from the reflected light at each wavelength. A processor applies a mathematical model to the image which compares the absorption of light by the biological tissue at a selected image point at each of the two spectral wavelengths to determine the volume-related parameters, such as the relative thickness and material properties, of the biological tissue at that location.
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Citations
34 Claims
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1. A system for determining volume-related parameters of a biological tissue, comprising:
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a light source for projecting light towards the biological tissue; a receiver for receiving light reflected from the biological tissue at two spectral wavelengths; an image acquisition system in communication with the receiver for forming an image from the reflected light at each wavelength; and a processor for applying a mathematical model to the image which compares the absorption of light by the biological tissue at a selected image point at each of the two spectral wavelengths to determine the volume-related parameters of the biological tissue at that location. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A system for determining a relative thickness at a location of an optic disc, comprising:
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a light source for projecting light towards the optic disc; a receiver for receiving light reflected from the optic disc at two spectral wavelengths; an image acquisition system in communication with the receiver for forming an image from the reflected light at each wavelength; and a processor for applying a mathematical model to the image which determines the difference between the absorption of light by the optic disc at a selected image point at each of the two spectral wavelengths to determine the relative thickness of the optic disc at that location. - View Dependent Claims (12, 13)
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14. A method for determining volume-related parameters of a biological tissue, comprising:
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illuminating the biological tissue with light; receiving light reflected from the biological tissue at two spectral wavelengths; forming an image from the reflected light at each wavelength; and applying a mathematical model to the image for comparing the absorption of light by the biological tissue at a selected image point at each of the two spectral wavelengths to determine the volume-related parameters of the biological tissue at that location. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A method for determining a relative thickness at a location of an optic disc, comprising:
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illuminating the optic disc with light; receiving light reflected from the optic disc at two spectral wavelengths; forming an image from the reflected light at each wavelength; and applying a mathematical model to the image for determining the difference between the absorption of light by the optic disc at a selected image point at each of the two spectral wavelengths to determine the relative thickness of the optic disc at that location. - View Dependent Claims (30, 31, 32, 33, 34)
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Specification