EXPANDABLE ENERGY DELIVERY DEVICES HAVING FLEXIBLE CONDUCTIVE ELEMENTS AND ASSOCIATED SYSTEMS AND METHODS

• US 20100160906A1
• Filed: 12/17/2009
• Published: 06/24/2010
• Est. Priority Date: 12/23/2008
• Status: Abandoned Application

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Asthmatx, Inc. (Boston Scientific Corporation)
• Inventors: Jarrard, Jerry
• Application Number:
  US12/640,644
• Publication Number:
  US 20100160906A1
• Time in Patent Office: Days
• US Class Current: 606/33
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00541 Lung or bronchi
• CPC Class Codes: A61B 2218/002 Irrigation

Abstract

Devices, systems, and methods are disclosed for providing energy to tissue in an internal passageway. An energy delivery device for treating an airway in a patient in accordance with one embodiment of the disclosure can include an elongated support configured to be passed through a lumen of a scope and a compliant inflatable member attached to the elongated support. The inflatable member is configured to move between a collapsed configuration and an expanded configuration. The energy delivery device can also include a flexible conductive element carried by the inflatable member. The flexible conductive element extends along a path and is configured to expand and contract longitudinally relative to the path as the inflatable member moves between the expanded and collapsed configurations.

Claims

1. An energy delivery device for treating an airway in a patient, the energy delivery device comprising:

an elongated support configured to be passed through a lumen of a scope;

a compliant inflatable member attached to the elongated support, the inflatable member being configured to move between a collapsed configuration and an expanded configuration; and

a flexible conductive element carried by the inflatable member, wherein the flexible conductive element extends along a path and is configured to expand and contract longitudinally relative to the path as the inflatable member moves between the expanded and collapsed configurations.

2. The energy delivery device of claim 1 wherein the flexible conductive element is elastic.

3. The energy delivery device of claim 1 wherein the flexible conductive element is disposed on an outer surface of the inflatable member, and wherein the flexible conductive element is an elastic conductor composed of a conductive ink having a binder and a conductive filler dispersed in the binder.

4. The energy delivery device of claim 3 wherein the conductive filler comprises electrically conductive flakes, fibers, strands, spheres, rods, cylinders, strips, pellets, or combinations thereof.

5. The energy delivery device of claim 3 wherein the conductive filler comprises silver, copper, carbon, or gold.

6. The energy delivery device of claim 3 wherein the conductive ink is applied to the outer surface of the inflatable member using a pen, a silk screen process, a spraying process, an ink jet printing process and/or a pad print process.

7. The energy delivery device of claim 1 wherein the flexible conductive element has:

a first resistance when the inflatable member is collapsed and the conductive element is in an initial state; and

a second resistance less than ten times the first resistance when the inflatable member is expanded and the conductive element is in a stretched state.

8. The energy delivery device of claim 1 wherein the airway comprises tissue, and wherein the flexible conductive element has a conductivity that is greater than a conductivity of the airway tissue when the inflatable member is in the expanded position and the conductive element is in a stretched state.

9. The energy delivery device of claim 1 wherein the flexible conductive element has:

a first conductivity when the inflatable member is collapsed and the conductive element is in an initial state; and

a second conductivity greater than the first conductivity when the inflatable member is expanded and the conductive element is in a stretched state.

10. The energy delivery device of claim 1 wherein the flexible conductive element is attached to an outer surface of the inflatable member in a helical or ring arrangement.

11. The energy delivery device of claim 1 wherein the flexible conductive element is attached to an outer surface of the inflatable member in an interdigitated arrangement having transverse finger portions and one or more longitudinal finger portions.

12. The energy delivery device of claim 1, further comprising a non-elongatable conductive element attached to the inflatable member and in electrical contact with the flexible conductive element.

13. The energy delivery device of claim 12 wherein the non-elongatable conductive element comprises a wire attached to the inflatable member and coupled to a distal end of the flexible conductive element.

14. The energy delivery device of claim 1 wherein the flexible conductive element is inelastic but expandable.

15. The energy delivery device of claim 14 wherein the flexible conductive element is a wire wrapped in a serpentine path around the inflatable member, and wherein the wire is configured to expand and contract longitudinally relative to the path in an accordion-like fashion as the inflatable member moves between the expanded and collapsed configurations.

16. The energy delivery device of claim 1 wherein the inflatable member is a non-conductive, non-porous balloon.

17. The energy delivery device of claim 1, wherein the flexible conductive element has a length in the range from about 5 mm to about 15 mm.

18. The energy delivery device of claim 1, further comprising a power source that provides RF energy in bipolar fields between adjacent flexible conductive elements.

19. An energy delivery device for treating an airway in a patient, the energy delivery device comprising:

an elongated support configured to be passed through a lumen of a scope;

a compliant inflatable member attached to the elongated support, the compliant inflatable member being configured to move between a collapsed configuration and an expanded configuration through a range of diameters of at least approximately 2 mm to 10 mm; and

an expandable electrode carried by the inflatable member, wherein the expandable electrode comprises a binder and a conductive material dispersed in the binder.

20. The energy delivery device of claim 19 wherein the expandable electrode is configured to longitudinally expand and contract with the compliant inflatable member between the expanded and collapsed configurations.

21. The energy delivery device of claim 19 wherein:

the binder is composed of an elastic polymer material; and

the conductive material is composed of gold, copper, carbon, or silver in the form of flakes, fibers, strands, spheres, rods, cylinders, strips, pellets or combinations thereof.

22. The energy delivery device of claim 19 wherein the conductive material dispersed in the binder includes a plurality of conductive particles at least approximately aligned with each other to minimize the resistance of the expandable electrode when the compliant inflatable member is in the expanded configuration.

23. The energy delivery device of claim 19 wherein the expandable electrode is disposed on an outer surface of the compliant inflatable member in a helical or ring arrangement.

24. The energy delivery device of claim 19 wherein the expandable electrode is disposed on an outer surface of the compliant inflatable member in an interdigitated arrangement having transverse finger portions and one or more longitudinal finger portions.

25. An energy delivery device for treating an airway in a patient, the energy delivery device comprising:

an elongated support configured to be passed through a lumen of a scope;

a compliant inflatable member attached to the elongated support, wherein the inflatable member is configured to move between a collapsed configuration and an expanded configuration; and

a stretchable electrode deposited directly on the inflatable member, wherein the stretchable electrode is configured to increase in length as the inflatable member moves from the collapsed configuration to the expanded configuration.

26. An energy delivery device for use in a body passageway, the energy delivery device comprising:

an elongated body having a proximal portion and a distal portion; and

an energy delivery unit at the distal portion of the elongated body, wherein the energy delivery unit comprises;

a compliant inflatable member moveable between a retracted configuration and an expanded configuration; and

one or more elongatable conductive elements disposed on an outer surface of the inflatable member, wherein the one or more conductive elements are positioned to contact a treatment area within the passageway when the inflatable member is in the expanded configuration.

27. A method for treating asthma, the method comprising:

inserting an energy delivery unit into an airway in a lung of a patient, the energy delivery unit including a compliant inflatable member attached to a distal portion of an elongated support and a flexible conductive element carried by the inflatable member, wherein the flexible conductive element is configured to expand and contract with the inflatable member as the inflatable member moves between a collapsed configuration and an expanded configuration;

expanding the inflatable member such that the flexible conductive element contacts a wall of the airway; and

delivering RF energy to the wall of the airway via the flexible conductive element in a bipolar manner.

28. The method of claim 27 wherein inserting an energy delivery unit into an airway and expanding the inflatable member comprises moving the inflatable member through a range of diameters of at least approximately 2 mm to 10 mm.

29. The method of claim 27 wherein delivering RF energy to the wall of the airway comprises circumferentially and longitudinally heating target tissue at a temperature in a range from about 65°

C. to about 70°

C. for an activation time period in a range from about 2 seconds to about 3 seconds.

30. The method of claim 29 wherein the target tissue comprises airway smooth muscle.

31. The method of claim 27 wherein delivering RF energy to the wall of the airway reduces airway smooth muscle tissue.

32. The method of claim 27, further comprising cooling a tissue layer adjacent to target tissue of the airway.

33. The method of claim 27 wherein cooling a tissue layer comprises at least partially filling the inflatable member with a liquid or a gas.

34. A method for manufacturing an energy delivery unit for treating an airway in a patient, the method comprising:

expanding a compliant inflatable member to a semi-expanded configuration, wherein the inflatable member is moveable through a range of diameters between a collapsed configuration and a fully expanded configuration; and

applying a conductive ink to an outer surface of the semi-expanded inflatable member, wherein the conductive ink comprises a binder and conductive filler particles dispersed in the binder.

35. The method of claim 34 wherein applying a conductive ink to an outer surface of the semi-expanded inflatable member comprises applying the conductive ink using a pen, a silk screen process, a spraying process, an ink jet printing process and/or a pad print process.

36. The method of claim 34 wherein applying a conductive ink to an outer surface of the semi-expanded inflatable member comprises applying the conductive ink in a helical or ring arrangement around the inflatable member.

37. The method of claim 34 wherein applying a conductive ink to an outer surface of the semi-expanded inflatable member comprises applying the conductive ink in an interdigitated arrangement around the inflatable member.