COLORIMETRIC SENSOR ARRAYS BASED ON NANOPOROUS PIGMENTS

• US 20100166604A1
• Filed: 09/02/2009
• Published: 07/01/2010
• Est. Priority Date: 09/04/2008
• Status: Active Grant

• Current Assignee: Board of Trustees of The University of Illinois
• Original Assignee: Board of Trustees of The University of Illinois
• Inventors: Kemling, Jonathan W., Feng, Liang, Lim, Sung H., Musto, Christopher J., Suslick, Kenneth S.
• Granted Patent: US 9,880,137 B2
• Time in Patent Office: Days
• US Class Current: 422/57
• CPC Class Codes: G01N 21/253 for batch operation, i.e. multisample apparatus analytical automats G01N35/00
• CPC Class Codes: G01N 21/78 producing a change of colour
• CPC Class Codes: G01N 31/22 using chemical indicators G01N31/02 takes precedence

Abstract

A colorimetric array includes a substrate, a first spot on the substrate, and a second spot on the substrate. The first spot includes a first nanoporous pigment that includes a first nanoporous material and a first immobilized, chemoresponsive colorant. The second spot includes a second nanoporous pigment that includes a second nanoporous material and a second immobilized, chemoresponsive colorant. The first nanoporous pigment is different from the second nanoporous pigment.

Claims

1. A colorimetric array comprising:

a substrate;

a first spot on the substrate, comprising a first nanoporous pigment,

the first nanoporous pigment comprising a first nanoporous material and a first immobilized, chemoresponsive colorant; and

a second spot on the substrate, comprising a second nanoporous pigment,

the second nanoporous pigment comprising a second nanoporous material and a second immobilized, chemoresponsive colorant;

where the first nanoporous pigment is different from the second nanoporous pigment.

2. The colorimetric array of claim 1, where the first immobilized, chemoresponsive colorant comprises a dye insolubilized by the first nanoporous material.

3. The colorimetric array of claim 2, where the dye is selected from the group consisting of a Lewis acid-base dye, a structure sensitive porphyrin, a pH sensitive dye, a solvatochromic dye, a vapochromic dye, a redox sensitive dye, and a metal ion sensitive dye.

4. The colorimetric array of claim 2, where the dye is a Lewis acid-base dye selected from the group consisting of a metal-ion containing dye, a boron-containing dye, a boronic acid containing dye, and a dye comprising an accessible heteroatom having a lone electron pair.

5. The colorimetric array of claim 4, where the dye is a metal-ion containing dye selected from the group consisting of a metalloporphyrin, a salen complex, a chlorin, a bispocket porphyrin, and a phthalocyanine.

6. The colorimetric array of claim 2, where the dye is a structure sensitive porphyrin selected from the group consisting of a tetrakis(2,4,6-trimethoxyphenyl)-porphyrin, a silylether-metalloporphyrin, and a siloxyl-substituted bis-pocket porphyrin.

7. The colorimetric array of claim 2, where the dye is a pH sensitive dye selected from the group consisting of a Brø

nsted acid dye and a Brø

nsted base dye.

8. The colorimetric array of claim 2, where the dye is responsive to at least one chemical interaction selected from the group consisting of Lewis acid-base interaction, Brø

nsted acid-base interaction, ligand binding, π

-π

complexation, hydrogen bonding, polarization, oxidation/reduction, and metal coordination.

9. The colorimetric array of claim 1, where the first immobilized, chemoresponsive colorant comprises a chemoresponsive pigment.

10. The colorimetric array of claim 9, where the chemoresponsive pigment is a porous pigment.

11. The colorimetric array of claim 1, where the first immobilized, chemoresponsive colorant comprises a chemoresponsive nanoparticle.

12. The colorimetric array of claim 11, where the chemoresponsive nanoparticle is selected from the group consisting of a nanoporous porphyrin solid, a semiconductor nanoparticle, and a metal nanoparticle.

13. The colorimetric array of claim 1, where the first and second nanoporous materials are the same, and the first and second immobilized, chemoresponsive colorants are different.

14. The colorimetric array of claim 1, where the first and second nanoporous materials are different, and the first and second immobilized, chemoresponsive colorants are the same.

15. The colorimetric array of claim 1, where the first and second nanoporous materials are different, and the first and second immobilized, chemoresponsive colorants are different.

16. The colorimetric array of claim 1, further comprising a plurality of additional spots on the substrate,

each spot of the plurality independently comprising a chemoresponsive colorant.

17. The colorimetric array of claim 16, where at least one spot of the plurality comprises an additional nanoporous pigment, different from the first and second nanoporous pigments.

18. The colorimetric array of claim 16, where each spot of the plurality independently comprises an additional nanoporous pigment, different from the first and second nanoporous pigments.

19. The colorimetric array of claim 18, where each additional nanoporous pigment of the plurality is different.

20. A method of making a colorimetric array, comprising:

depositing a first liquid at a first point on a substrate,

depositing a second liquid at a second point on a substrate,

converting the first liquid into a first spot on the substrate, and

converting the second liquid into a second spot on the substrate;

where the first spot comprises a first nanoporous pigment comprising a first nanoporous material and a first immobilized, chemoresponsive colorant, and

the second spot comprises a second nanoporous pigment comprising a second nanoporous material and a second immobilized, chemoresponsive colorant, and

the first nanoporous pigment is different from the second nanoporous pigment.

21-54. -54. (canceled)