METHODS AND SYSTEMS FOR PROSTATE HEALTH MONITORING
First Claim
1. A method of detecting prostate enlargement comprising:
- a) monitoring a prostate biomarker value at one or more times;
b) measuring a volume of the prostate of the subject when the prostate biomarker value is or exceeds a target value;
c) calibrating the prostate biomarker value with the volume measurement; and
d) detecting the presence or absence of prostate enlargement in the subject by measuring the prostate biomarker value.
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Abstract
Disclosed herein are computer-implemented personalized probabilities determination systems and methods for use in integrated health systems and methods related to the medical conditions, such as conditions of the prostate, including benign and malignant disease. A system and method is disclosed herein for estimating trends in biomarkers and calculating the probability of different prostate medical conditions. Also disclosed herein are methods and systems relating to estimating prostate volume and probabilities of benign prostatic hyperplasia (BPH). Methods and systems relating to probabilities and feedback during treatment of prostatic conditions or diseases are also provided herein.
53 Citations
46 Claims
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1. A method of detecting prostate enlargement comprising:
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a) monitoring a prostate biomarker value at one or more times; b) measuring a volume of the prostate of the subject when the prostate biomarker value is or exceeds a target value; c) calibrating the prostate biomarker value with the volume measurement; and d) detecting the presence or absence of prostate enlargement in the subject by measuring the prostate biomarker value. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method of performing a course of medical action for prostate enlargement in a subject, the method comprising:
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a) monitoring a prostate biomarker value from a subject at one or more times; b) measuring a volume of the prostate of the subject when the prostate biomarker value is or exceeds a target value; c) calibrating the prostate biomarker value with the volume measurement; d) estimating the volume of the prostate by measuring the prostate biomarker value at a time after the measuring step; e) performing a course of medical action when the estimated volume of the prostate is greater than a threshold value. - View Dependent Claims (9, 10, 11, 12, 13, 14, 15, 16, 18, 19, 20, 21, 22, 23, 24)
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17. The method of claim 17, wherein the monitoring step comprises eliminating anomalous prostate biomarker values from the trend that are values outside of a tolerance.
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25. A method comprising:
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a) establishing a Bayesian network comprising a plurality of prostatitis conditions of the prostate, wherein the priors of the Bayesian network are provided by historical data; b) calculating a probability of a target prostatitis condition of a prostate using a trend of a prostate biomarker value over time; c) providing the probability of the target medical condition of the prostate to the Bayesian network as a prior for the target medical condition; d) performing a course of medical action in respect to the target medical condition and receiving the result of the course of medical action; e) adjusting the priors of the Bayesian network according to the result; and f) calculating the probability of the target prostatitis condition. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33)
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34. A method of providing a medical treatment of a prostate condition comprising:
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a) providing a course of medical action to a subject with a prostate condition; b) detecting a change in a prostate biomarker value of the subject before providing the medical treatment and during the medical treatment; and c) adjusting the course of medical action based upon the change in the prostate biomarker value. - View Dependent Claims (35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
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Specification