Method and apparatus for determining and delivering a drug bolus

• US 20100168660A1
• Filed: 12/23/2009
• Published: 07/01/2010
• Est. Priority Date: 06/29/2007
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics International Ltd.
• Inventors: Weinert, Stefan, Hellwig, Robert, Galley, Paul J., Zivitz, Maury
• Granted Patent: US 8,118,770 B2
• Time in Patent Office: Days
• US Class Current: 604/66
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2209/01 Remote controllers for specific apparatus
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: G06F 1/1626 with a single-body enclosure integrating a flat display, e.g. Personal Digital Assistants [PDAs]
• CPC Class Codes: G06F 1/169 the I/O peripheral being an integrated pointing device, e.g. trackball in the palm rest area, mini-joystick integrated between keyboard keys, touch pads or touch stripes G06F1/1643 takes precedence; constructional details of pointing devices G06F3/033
• CPC Class Codes: G06F 1/1698 the I/O peripheral being a sending/receiving arrangement to establish a cordless communication link, e.g. radio or infrared link, integrated cellular phone details of antennas disposed inside a computer H01Q1/2266
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

An electronic device may be configured to prompt a user via an on-board display to measure user glucose via an on-board glucose meter, to compute a first drug bolus value based on the measured user glucose, to display the first drug bolus value on the display and prompt the user via the display to enter carbohydrate information into the device, to compute a second drug bolus value based on the entered carbohydrate information, to display the second drug bolus value on the display and prompt the user via the display to enter user health information into the device, to compute a third drug bolus value based on the entered health information and a total drug bolus value as a sum of the first, second and third drug bolus values, and to display the third and total drug bolus values on the display.

Claims

1. A method for determining a drug bolus for a user via an electronic device including an on-board glucose meter and a display, the method comprising:

displaying a bolus recommendation screen on the display unit,

including in the bolus recommendation screen a glucose value field for displaying glucose values of the user that are measured by the on-board glucose meter and automatically entered into the glucose value field,

including in the bolus recommendation screen a carbohydrate field for displaying carbohydrate information entered into the electronic device, the carbohydrate information corresponding to carbohydrate contents of meals or snacks taken or planned to be taken by the user,

including in the bolus recommendation screen a health field for displaying health information entered into the electronic device, the health information corresponding to a health condition or activity of the user, and

including in the bolus recommendation screen a total bolus field for displaying based on the values in the glucose value field, the carbohydrate field and the health field.

2. The method of claim 1 further comprising,

prompting the user to measure glucose concentration of body fluid of the user via the on-board glucose meter if at least a time period has elapsed since last measuring the glucose concentration of the body fluid of the user, and

displaying subsequently measured glucose concentration of the user in the glucose value field.

3. The method of claim 2 further comprising displaying no glucose concentration value in the glucose value field if the user does not measure glucose concentration via the on-board glucose meter in response to the prompt to measure glucose concentration of body fluid of the user via the on-board glucose meter.

4. The method of claim 2 further comprising displaying in the glucose value field the most recent glucose concentration of the user that was measured by the on-board glucose meter if the at least a time period has not elapsed since last measuring the glucose concentration of the body fluid of the user.

5. The method of claim 1 wherein the electronic device comprises a plurality of user buttons,

and wherein the method further comprises entering the carbohydrate information via into the electronic device via one or more of the plurality of user buttons.

6. The method of claim 1 wherein the electronic device comprises a plurality of user buttons,

and wherein the method further comprises entering the health information into the electronic device via one or more of the plurality of user buttons.

7. The method of claim 6 wherein the health field includes a plurality of health descriptions,

and wherein the user enters the health information into the electronic device by selecting one of the plurality of health descriptions via the one or more of the plurality of user buttons.

8. The method of claim 7 wherein the plurality of health descriptions includes a no selection and at least one of exercise, stress and illness.

9. The method of claim 1 wherein the electronic device comprises a plurality of user buttons,

and wherein the method further comprises including in the bolus recommendation screen a confirmation indicator that the user can select via at least one of the plurality of user buttons to confirm delivery of the total recommended bolus value displayed in the total bolus field.

10. The method of claim 9 wherein each of the glucose value field, the carbohydrate field and the health field are repeatedly accessible until the confirmation indicator is selected.

11. The method of claim 1 wherein the electronic device comprises a wireless communication circuit,

and wherein the method further comprises transmitting a command via the wireless communication circuit to command a liquid infusion pump to deliver a bolus in the amount of the total recommended bolus value displayed in the total bolus field.

12. The method of claim 1 further comprising including in the bolus recommendation screen a bolus type field for displaying a bolus type entered into the electronic device, the bolus type corresponding to a type of bolus delivery.

13. The method of claim 12 wherein the electronic device comprises a plurality of user buttons,

and wherein the method further comprises entering the bolus type into the electronic device via one or more of the plurality of user buttons.

14. The method of claim 13 wherein the bolus type field includes a plurality of bolus type choices,

and wherein the user enters the bolus type into the electronic device by selecting one of the plurality bolus type choices via the one or more of the plurality of user buttons.

15. The method of claim 14 wherein the plurality of bolus type choices includes a standard bolus, a multi-wave bolus, an extended bolus, a manually programmed pump bolus and a bolus manually delivered via a pen or syringe.

16. A medical system, comprising:

a liquid infusion pump including a first processor and a first wireless communication circuit for receiving remotely generated commands, the first processor including a memory having instructions stored therein that are executable by the first processor to control the liquid infusion pump to deliver liquid to a body of a user, and

a remote electronic device including an on-board blood glucose meter, a second processor and a second wireless communication device for transmitting wireless commands, the second processor executing a bolus recommendation process that recommends a bolus amount based on one or more of blood glucose measurements made by the on-board glucose meter, carbohydrate values entered by a user and corresponding to carbohydrate values of meals or snacks, and health information entered by the user and corresponding to health activities or conditions of the user, the second processor including a memory having instructions stored therein that are executable by the second processor to send via the second wireless communication circuit a wireless command to deliver a bolus in the amount of the recommended bolus amount when the user confirms selection of the recommended bolus amount,

wherein the liquid infusion pump is responsive to the wireless command to deliver insulin in the amount of the user confirmed recommended bolus amount.

17. A method of remotely commanding via a remote electronic device delivery of an amount of liquid by a liquid infusion pump, the method comprising:

determining with the remote electronic device an amount of liquid to be immediately delivered by the pump,

sending a wireless command by the remote electronic device to deliver the amount of liquid to be immediately delivered,

displaying on a display device of the remote electronic device the amount of liquid to be immediately delivered by the pump,

delivering with the pump the amount of liquid to be immediately delivered after receiving the wireless command from the remote electronic device,

periodically sending wireless commands by the pump to the remote electronic device of delivery information when the pump is delivering the amount of liquid to be immediately delivered, the delivery information corresponding to incremental quantities of the amount of liquid that has been delivered by the liquid infusion pump, and

controlling the display device of the remote electronic device to incrementally count down from the amount of liquid to be immediately delivered based on the delivery information periodically sent by the pump.

18. A method of determining active insulin in a user taking insulin via an ambulatory infusion pump, the method comprising:

receiving delivery information from the pump corresponding to insulin delivered to the user via the pump,

computing from the delivery information active insulin in the user by adding together amounts of insulin delivered by the pump over a time period, and

displaying the active insulin via a display device.

19. A method for determining a drug bolus for a user via an electronic device including an on-board glucose meter and a display, the method comprising:

determining a first bolus amount based on blood glucose measurements made by the on-board glucose meter,

selecting food items for a meal or snack from a food database on-board the electronic device,

automatically computing carbohydrate values of each selected food item,

automatically determining a total carbohydrate value corresponding to a sum of carbohydrate values of each selected food item,

determining a second bolus amount based on the total carbohydrate value,

determining a third bolus amount based on health information entered by the user and corresponding to health activities or conditions of the user, and

determining a total recommended bolus amount based on the first, second and third bolus amounts.

20. The method of claim 19 further comprising delivering a drug bolus to the user in the amount of the total recommended bolus amount.