Methods and Apparatus for Applying Energy to Patients

• US 20100174340A1
• Filed: 01/05/2010
• Published: 07/08/2010
• Est. Priority Date: 04/18/2006
• Status: Abandoned Application

• Current Assignee: Electrocore, Llc
• Original Assignee: electroCore, Inc.
• Inventors: Simon, Bruce J.
• Application Number:
  US12/652,302
• Publication Number:
  US 20100174340A1
• Time in Patent Office: Days
• US Class Current: 607/40
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes

Abstract

The present invention provides systems, apparatus and methods for selectively applying electrical energy to body tissue. More specifically, systems and methods are provided for introducing a flowable electrode to a target site within the patient such that the flowable electrode converts to a hardened electrode after being introduced to the target site. An electrical impulse is applied to the hardened electrode to modulate one or more nerve(s) at the target site. The electrode preferably comprises a conductive polymer material.

Claims

1. A device for delivering electrical energy to a patient, comprising:

an electrode comprising an electrically conductive material configured to convert from a flowable state to a hardened state;

an introducer configured to introduce the electrode in the flowable state to a target site in the patient; and

a source of electrical energy coupled to the electrode for delivering an electrical impulse to the electrode in the hardened state.

2. The device of claim 1 wherein the electrode is configured to convert to the hardened state at body temperature.

3. The device of claim 1 wherein the electrode comprises first and second materials and is configured to convert to the hardened state upon contact between the first and second materials.

4. The device of claim 1 wherein the electrode comprises a conductive polymer.

5. The device of claim 4 wherein the conductive polymer comprises an electrically conductive solution.

6. The device of claim 1 wherein the introducer comprises a needle configured to inject the electrode in the flowable state to the target site.

7. The device of claim 6 wherein the needle is configured for advancement between first and second vertebral bones into an epidural space of the patient.

8. The device of claim 1 further comprising an electrical connector for coupling the source of electrical energy to the electrode.

9. The device of claim 1 wherein the electrode comprises a resorbable material.

10. The device of claim 1 wherein the electrode comprises a nondegradable material configured for implantation in the patient.

11. The device of claim 1 wherein the electrode is sized and shaped in the hardened state to conform to a target region in the epidural space of the patient.

12. The device of claim 1 wherein the electrode is sized and shaped in the hardened state to conform to a target region on a nerve.

13. The device of claim 1 wherein the electrode is sized and shaped in the hardened state to conform to a target region on a vagus nerve.

14. The device of claim 1 wherein the introducer is configured to inject the electrode in the flowable state through a percutaneous penetration in the patient.

15. The device of claim 1 wherein the source of electrical energy is an electrical signal generator operating to apply at least one electrical signal to the electrode, the electrical signal having a frequency between about 1 Hz to 3000 Hz, a pulse duration of between about 10-1000 us, and an amplitude of between about 1-20 volts.

16. The device of claim 1 further comprising an electrical contact sized and shaped for positioning within the electrode.

17. A method for treating an ailment in a patient comprising:

introducing a flowable electrode to a target site within the patient such that the flowable electrode changes to a hardened electrode after being introduced to the target site; and

applying an electrical impulse to the hardened electrode to modulate one or more nerve(s) at the target site.

18. The method of claim 17 wherein the introducing step is carried out by injecting first and second materials to the target site such that the first and second materials contact each other and convert to the hardened electrode.

19. The method of claim 17 wherein the introducing step comprises injecting a flowable material that hardens at body temperature to the target site.

20. The method of claim 17 wherein the introducing step comprises injecting the flowable electrode through a percutaneous penetration in the patient.

21. The method of claim 17 further comprising electrically coupling the hardened electrode to a source of electrical energy.

22. The method of claim 21 wherein the electrically coupling step is carried out by positioning an electrical contact within the flowable electrode at the target site before the flowable electrode changes to the hardened electrode.

23. The method of claim 17 wherein the introducing step comprises introducing the flowable electrode to a target site within an epidural space of the patient such that the hardened electrode contacts a dura within the epidural space.

24. The method of claim 17 wherein the introducing step comprises advancing a needle through a spinal ligament between first and second vertebral bones and injecting the flowable electrode directly into the epidural space.

25. The method of claim 17 wherein the introducing step comprises introducing the flowable electrode to a target site on a nerve within the patient such that the hardened electrode substantially conforms to the nerve.

26. The method of claim 25 wherein the nerve is a vagus nerve.

27. The method of claim 17 further comprising contacting a return electrode to an external portion of the patient and emanating an electro-magnetic field from the hardened electrode through the patient to the return electrode.

28. The method of claim 17 wherein the applying step comprises applying an electrical impulse to a sympathetic nerve of a patient to modulate nerve signals thereof such that intestinal peristalsis function within the patient is at least partially improved.

29. The method of claim 17 wherein the applying step is carried out by applying an electrical signal to the hardened electrode of a frequency between about 10 Hz to 200 Hz, a pulse duration of between about 20-400 us, and an amplitude of between about 1-20 volts.

30. The method of claim 17 wherein the applying step is carried out by applying an electrical impulse to the electrode sufficient to increase an intestinal motility of the patient.

31. The method of claim 17 wherein the applying step is carried out by applying an electrical impulse to the electrode sufficient to increase a gastric motility of the patient.

32. The method of claim 17 wherein the applying step is carried out by applying an electrical impulse to the electrode sufficient to treat pain.

33. The method of claim 32 wherein the pain is visceral pain associated with irritable bowel syndrome.