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POLYMERS WITH BIO-FUNCTIONAL SELF ASSEMBLING MONOLAYER ENDGROUPS FOR THERAPEUTIC APPLICATIONS AND BLOOD FILTRATION

  • US 20100179284A1
  • Filed: 05/28/2008
  • Published: 07/15/2010
  • Est. Priority Date: 05/30/2007
  • Status: Abandoned Application
First Claim
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1. An in vitro, ex vivo, or in vivo medical device or prosthesis or packaging assembly comprising a polymer body comprising at least one polymer having the formula
R(LE)x whereinR is a polymeric core having a number average molecular weight of from 5,000 to 7,000,000 daltons, and having x endgroups,x is an integer≧

  • 1,E is an endgroup covalently linked to polymeric core R by linkage L,L is a divalent oligomeric chain having at least 5 repeat units and is capable of self-assembly with L chains on adjacent molecules of the polymer, and the moieties L and/or E in the polymer(s) may be the same as or different from one another in composition and/or molecular weight, wherein the polymer body comprises a plurality of polymer molecules located internally within said body, at least some of which internal polymer molecules have endgroups that comprise a surface of the body, wherein the surface endgroups include at least one self-assembling moiety.

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