RAPIDLY ERODING ANCHOR

• US 20100179589A1
• Filed: 01/08/2010
• Published: 07/15/2010
• Est. Priority Date: 01/09/2009
• Status: Abandoned Application

• Current Assignee: Abbott Vascular Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Vascular Incorporated (Abbott Laboratories Incorporated)
• Inventors: Roorda, Wouter E., McCrystle, Kelly J., Voss, Laveille K., Osman, Karim S.
• Application Number:
  US12/684,569
• Publication Number:
  US 20100179589A1
• Time in Patent Office: Days
• US Class Current: 606/213
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61B 2017/0061 Implements located only on one side of the opening
• CPC Class Codes: A61B 2017/00623 Introducing or retrieving devices therefor
• CPC Class Codes: A61B 2017/00637 for sealing trocar wounds through abdominal wall
• CPC Class Codes: A61B 2017/00654 entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2017/00659 located only on one side of the opening
• CPC Class Codes: A61B 2017/00663 the implement being a suture
• CPC Class Codes: A61B 2017/00668 the implement being a tack or a staple
• CPC Class Codes: A61L 2400/04 Materials for stopping bleeding
• CPC Class Codes: A61L 31/042 Polysaccharides
• CPC Class Codes: A61L 31/048 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

An anchor for using a closure device includes a body being configured to move from a pre-deployed state to a deployed state. In the pre-deployed state, the body has a first width aspect relative to a direction of deployment and a second width aspect in the deployed state relative to the direction of deployment, the second width aspect being greater than the first width aspect and wherein the body is formed from a rapidly eroding material configured to erode through dissolution within a body lumen.

Claims

1. An anchor for using a closure device, the anchor comprising:

a body being configured to move from a pre-deployed state to a deployed state, wherein in the pre-deployed state the body has a first width aspect relative to a direction of deployment and a second width aspect in the deployed state relative to the direction of deployment, the second width aspect being greater than the first width aspect and wherein the body is formed from a rapidly eroding material configured to erode through dissolution within a body lumen.

2. The anchor of claim 1, wherein the body is configured to erode in less than twelve hours.

3. The anchor of claim 1, wherein the body is configured to erode in less than one hour.

4. The anchor of claim 1, wherein the body includes a major axis and wherein the body is configured to rotate in response to a force applied parallel to the major axis.

5. The anchor of claim 1, wherein the rapidly eroding material includes at least one of a sugar and a sugar-derivative.

6. The anchor of claim 5, wherein the sugar derivative includes sugar alcohols including mannitol, sorbitol, and isomalt.

7. The anchor of claim 5, wherein the sugar includes at least one of a group including glucose, fructose, lactose and maltose.

8. The anchor of claim 1, wherein the body further includes at least one polymeric component.

9. The anchor of claim 8, wherein the polymeric component includes at least one of poly-vinylpyrrolidone, poly-ethyleneglycol, hydroxyethyl starch, dextran or dextran sulfate.

10. The anchor of claim 1, wherein the rapidly eroding material is water soluble.

11. The anchor of claim 1, wherein the rapidly eroding material forms a crystalline matrix.

12. The anchor of claim 1, wherein the rapidly eroding material forms a glass structure.

13. The anchor of claim 1, wherein the rapidly eroding material includes a plurality of pores.

14. The anchor of claim 13, wherein at least one of the pores includes at least one beneficial agent.

15. The anchor of claim 13, wherein the anchor member includes at least one of poly-vinyl pyrrolidone, hyaluronic acid, dextran, hydrogel, heparin, and benzalkonium heparin.

16. The closure device of claim 1, wherein the anchor member is formed using a freeze-drying process.

17. A method of closing a puncture in a wall of a body lumen, comprising:

advancing an anchor in a deployment direction through the anchor, the anchor having a first width aspect relative to the deployment direction;

deploying the anchor distally of the wall of the body lumen to cause the anchor to move to have a second width aspect relative to the deployment direction, the second width aspect being larger than the first width aspect;

drawing the anchor distally into engagement with a distal side of the wall of the body lumen; and

deploying a closure element into the wall of the body lumen, wherein the anchor is formed from a rapidly eroding material that dissolves in the body lumen in less than twelve hours.

18. The method of claim 17, wherein rapidly eroding material dissolves in the body lumen in less than one hour.

19. The method of claim 17, wherein deploying a closure element includes deploying an expandable plug.

20. The method of claim 17, wherein deploying a closure element includes deploying tines into the wall of the body lumen.

21. A closure device system comprising:

a delivery sheath;

a rapidly eroding anchor at least partially disposed within the delivery sheath in an initial configuration, the closure member comprising one or more sugars;

a suture element coupled to the closure member and disposed at least partially through the delivery sheath; and

a pusher disposed at least partially within the delivery sheath and configured to deploy the anchor member from a distal end of the delivery sheath.

22. The closure device system of claim 21, further comprising an expandable plug configured to be positioned between the anchor and the pusher.

23. The closure device system of claim 21, further comprising an expandable closure element configured to be moved between an expanded state and a restricted state to close a puncture in a wall of a body lumen.