Vascular Graft With Kink Resistance After Clamping
First Claim
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1. A self-sealing vascular graft, comprising:
- a generally tubular ePTFE substrate, including a proximal end section, a distal end section and a central section positioned between the proximal end section and distal end section, at least one of the proximal end section, central section, and distal end section including a self-sealing region; and
a first beading contiguous to a surface of the ePTFE substrate along at least a portion of the central section.
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Abstract
A self-sealing vascular graft with kink resistance is described. The vascular graft includes a substrate that can be a PTFE, having a self-sealing region that may include several layers of material. The central section of the vascular graft may be constructed differently from surrounding self-sealing regions, in order to provide kink resistance following the clamping of the graft. Also described is a graft with a flared cuff attached to one or both ends, the attachment or transition region including reinforcement beading.
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Citations
62 Claims
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1. A self-sealing vascular graft, comprising:
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a generally tubular ePTFE substrate, including a proximal end section, a distal end section and a central section positioned between the proximal end section and distal end section, at least one of the proximal end section, central section, and distal end section including a self-sealing region; and a first beading contiguous to a surface of the ePTFE substrate along at least a portion of the central section. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A vascular graft, comprising:
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a generally tubular ePTFE substrate defining a longitudinal axis; a layer of polyurethane matrix disposed about the ePTFE substrate; and a first beading disposed in the polyurethane matrix. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23)
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24. A method of making a kink resistant vascular graft, comprising:
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providing a generally tubular ePTFE substrate, including a proximal end section, a distal end section and a central section positioned between the proximal end section and distal end section; and bonding a first beading to a surface of the ePTFE substrate along at least a portion of the central section. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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39. A self-sealing vascular cuff graft, comprising:
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a generally tubular ePTFE substrate; a self-sealing region extending along a length of the generally tubular substrate between a first and second end thereof, the self-sealing region including at least one of a sealant layer and a foam layer; an outer ePTFE member positioned over at least a portion of the self-sealing region; a first beading positioned over the substrate at the first end adjacent to the self-sealing region, the outer ePTFE member extending over at least a portion of the first beading; a second beading positioned over the outer ePTFE member at the first end adjacent to the self-sealing region; and a flared vascular cuff having a proximal end positioned over at least a portion of the first and second beadings. - View Dependent Claims (40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52)
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53. A vascular graft, comprising:
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a generally tubular ePTFE substrate defining a longitudinal axis extending through distal portions of the ePTFE substrate, the ePTFE substrate having a first cross-sectional area about the longitudinal axis; and an elastomeric member disposed about the ePTFE substrate so that, as the ePTFE substrate is curved to contact the distal portions of the substrate to a generally circular pin having a diameter of about 20 millimeters or less, the ePTFE includes a second cross-sectional area of the ePTFE substrate of at least about 50% of the first cross-sectional area where the second cross-sectional area is located approximately 20 millimeters from the outer surface of the circular pin. - View Dependent Claims (54, 55)
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56. A method of making a self-sealing vascular cuff graft, comprising:
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providing a generally tubular ePTFE substrate, including a self-sealing region extending along a length of the generally tubular substrate between a first and second end thereof; positioning a first beading over the substrate at the first end adjacent to the self-sealing region; disposing an outer ePTFE member over at least a portion of the self-sealing region and the first beading; positioning a second beading over the outer ePTFE member at the first end adjacent to the self-sealing region; and attaching a flared vascular cuff to the substrate over at least a portion of the first and second beadings. - View Dependent Claims (57, 58, 59, 60, 61, 62)
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Specification