Integrated High Throughput System for the Analysis of Biomolecules
First Claim
1. An affinity microcolumn comprising a high surface area material comprising a phase separable metal, which has high flow properties and a low dead volume, contained within a housing and affinity reagents bound to the surface of the high surface area material, wherein the affinity reagents are either activated or activatable and the high surface area is formed by thermal surface phase separation of the metal and leaching one of the separated soluble phases to result in a pore formation.
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Abstract
Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules.
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Citations
10 Claims
- 1. An affinity microcolumn comprising a high surface area material comprising a phase separable metal, which has high flow properties and a low dead volume, contained within a housing and affinity reagents bound to the surface of the high surface area material, wherein the affinity reagents are either activated or activatable and the high surface area is formed by thermal surface phase separation of the metal and leaching one of the separated soluble phases to result in a pore formation.
Specification