SURGICAL MICROSCOPE FOR OBSERVING AN INFRARED FLUORESCENCE AND CORRESPONDING METHOD

• US 20100182418A1
• Filed: 12/16/2009
• Published: 07/22/2010
• Est. Priority Date: 12/17/2008
• Status: Active Grant

• Current Assignee: Carl Zeiss Meditec AG (Carl-Zeiss-Stiftung)
• Original Assignee: Carl Zeiss Surgical GmbH (Carl-Zeiss-Stiftung)
• Inventors: Quendt, Dieter, Steffen, Joachim, Nahm, Werner, Jess, Helge
• Granted Patent: US 8,659,651 B2
• Time in Patent Office: Days
• US Class Current: 348/79
• CPC Class Codes: G02B 21/0012 Surgical microscopes counterbalanced structures for surgical microscopes G02B7/001
• CPC Class Codes: G02B 21/0064 multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling G02B21/0076 takes precedence
• CPC Class Codes: G02B 21/0076 arrangements using fluorescence or luminescence
• CPC Class Codes: G02B 21/16 adapted for ultraviolet illumination ; Fluorescence microscopes G02B21/0076 takes precedence
• CPC Class Codes: G02B 21/22 Stereoscopic arrangements
• CPC Class Codes: G02B 27/1013 for colour or multispectral image sensors, e.g. splitting an image into monochromatic image components on respective sensors spectral imaging systems G01J
• CPC Class Codes: G02B 27/144 using partially transparent surfaces without spectral selectivity G02B27/147 takes precedence
• CPC Class Codes: G02B 27/145 having sequential partially reflecting surfaces
• CPC Class Codes: G02B 27/149 using crossed beamsplitting surfaces, e.g. cross-dichroic cubes or X-cubes

Abstract

A surgical microscope for observing an infrared fluorescence includes a camera system 25 having three chips, wherein infrared light emanating from an object is supplied to only one of the three camera chips via a dichroic beam splitter.

Claims

1. A surgical microscope for observing an infrared fluorescence, the surgical microscope comprising:

a camera system having an input port, a dichroic beam splitter and first, second and third camera chips, wherein the dichroic beam splitter is configured to direct red light received at the input port mainly towards the first camera chip via a first output port of the beam splitter, to direct green light received at the input port mainly towards the second camera chip via a second output port of the beam splitter, to direct blue light received at the input port mainly towards the third camera chip via a third output port of the beam splitter, and to direct infrared light received at the input port mainly only towards one of the first, second and third camera chips;

microscopy optics configured to optically image an object area onto the camera chips of the camera system; and

a display system configured to display images based on light intensities detected by the camera chips of the camera system.

2. The surgical microscope according to claim 1 wherein the beam splitter is configured to direct the infrared light received at the input port mainly only towards one of the second and third camera chips.

3. The surgical microscope according to claim 1 further comprising a first blocking filter substantially blocking infrared light, wherein the blocking filter is operable to be selectively positioned inside or outside of an imaging beam path between the object area and the input port of the dichroic beam splitter.

4. The surgical microscope according to claim 3 further comprising:

a second blocking filter substantially blocking at least one of red light, green light and blue light, wherein the second blocking filter is operable to be selectively positioned inside or outside of an imaging beam path between the image area and the input port of the dichroic beam splitter; and

an actuating system coupled to the first and second blocking filters and configured such that only one of the first and second blocking filters is positioned in the imaging beam path at a given time.

5. The surgical microscope according to claim 3 further comprising:

an illumination system configured to direct at least one illumination light beam towards the object area;

a third blocking filter substantially blocking at least one of red light, green light and blue light, wherein the third blocking filter is operable to be selectively positioned inside or outside of a beam path of the illumination system; and

an actuating system coupled to the first and third blocking filters and configured such that only one of the first and third blocking filters is positioned in the imaging beam path and the beam path of the illumination system, respectively, at a given time.

6. The surgical microscope according to claim 1 further comprising a blocking filter substantially blocking at least one of red light, green light and blue light, wherein the blocking filter is operable to be selectively positioned inside or outside of an imaging beam path between the object area and the input port of the dichroic beam splitter.

7. The surgical microscope according to claim 1 further comprising:

an illumination system configured to direct at least one illumination light beam towards the object area; and

a blocking filter substantially blocking at least one of red light, green light and blue light, wherein the blocking filter is operable to be selectively positioned inside or outside of a beam path of the illumination system.

8. The surgical microscope according to claim 1 wherein the dichroic beam splitter is further configured such that, when the red light, which is mainly directed towards the first camera chip, is supplied to the input port of the dichroic beam splitter, a ratio of a light intensity detected by the first detector and a sum of a light intensity detected by the second detector and a light intensity detected by the third detector is greater than one of 1.8, 2.5 and 3.0;

wherein the dichroic beam splitter is further configured such that, when the green light, which is mainly directed towards the second camera chip, is supplied to the input port of the dichroic beam splitter, a ratio of a light intensity detected by the second detector and a sum of a light intensity detected by the first detector and a light intensity detected by the third detector is greater than one of 1.8, 2.5 and 3.0; and

wherein the dichroic beam splitter is further configured such that, when the blue light, which is mainly directed towards the third camera chip, is supplied to the input port of the dichroic beam splitter, a ratio of a light intensity detected by the third detector and a sum of a light intensity detected by the first detector and a light intensity detected by the second detector is greater than one of 1.8, 2.5 and 3.0.

9. The surgical microscope according to claim 1 wherein the dichroic beam splitter is further configured such that, when the infrared light, which is mainly directed towards only one of the first, second and third camera chips, is supplied to the input port of the dichroic beam splitter, a ratio of a light intensity detected by the one of the first, second and third camera chips and a sum of light intensities detected by the other ones of the first, second and third camera chips is greater than one of 1.8, 2.5 and 3.0.

10. The surgical microscope according to claim 1 wherein the infrared light includes light of a wavelength range from 800 nm to 930 nm.

11. The surgical microscope according to claim 1 wherein the blue light includes light of a wavelength range from 440 nm to 490 nm, wherein the green light includes light of a wavelength range from 520 nm to 570 nm, and wherein the red light includes light of a wavelength range from 625 nm to 740 nm.

17. The microscopy method according to claim 12 wherein the method is performed using the surgical microscope according to claim 1.

12. A microscopy method comprising:

operating a microscope in a first mode of operation, the first mode of operation comprising;

supplying light including red, green and blue light to an object;

supplying red light emanating from the object to a first camera chip,

supplying green light emanating from the object to a second camera chip, and

supplying blue light emanating from the object to a third camera chip; and

operating the microscope in a second mode of operation, the second mode of operation comprising;

exciting a fluorescence at the object, and

supplying infrared light generated by the fluorescence from the object mainly to only one of the first, second, or third camera chips.

13. The microscopy method according to claim 12 further comprising blocking infrared light from being supplied to one of the first, second, or third camera chips in only the first mode of operation.

14. The microscopy method according to claim 12 further comprising blocking light having wavelengths greater than 700 nm and smaller than 805 nm from being supplied to one of the first, second, or third camera chips in the second mode of operation.

15. The microscopy method according to claim 12 further comprising blocking one of red, green, or blue light from being supplied to one of the first, second, or third camera chips in the second mode of operation.

16. The microscopy method according to claim 12 further comprising supplying at most two of red light, green light, or blue light to the object in the second mode of operation.