FLUID DELIVERY SYSTEMS, DEVICES AND METHODS FOR DELIVERY OF HAZARDOUS FLUIDS

• US 20100185040A1
• Filed: 03/29/2010
• Published: 07/22/2010
• Est. Priority Date: 04/08/2003
• Status: Active Grant

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Medrad Incorporated (Bayer AG)
• Inventors: Uber, Arthur E. III, Reilly, David M., Griffiths, David M., Hirschman, Alan D., Trombley, Frederick W.
• Granted Patent: US 8,454,561 B2
• Time in Patent Office: Days
• US Class Current: 600/5
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2202/049 Toxic
• CPC Class Codes: A61M 25/0045 multi-layered, e.g. coated coating materials A61L29/08
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1408 in parallel, e.g. manifolds, sequencing valves access sites A61M39/02; tube connectors A61M39/10
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/44 having means for cooling or heating the devices or media
• CPC Class Codes: A61N 5/1001 using radiation sources introduced into or applied onto the body; brachytherapy

Abstract

A system for injecting a patient, includes a container enclosing a hazardous pharmaceutical; a first pump to deliver a hazardous pharmaceutical to a patient and a fluid path operably connected to the first pump, the container, and the patient. The system further includes a hazardous material containment suitable to confine the hazardous pharmaceutical during connection of the hazardous pharmaceutical container to the fluid path.

Claims

1. An assembly for connection to an injector comprising a retention mechanism to retain the assembly and a pressurizing mechanism to pressurize one or more fluids within the assembly for delivery to a patient, the assembly comprising:

at least a first compartment defining an enclosure adapted to enclose a hazardous pharmaceutical container enclosing a hazardous pharmaceutical, the first compartment being adapted to prevent hazardous materials from escaping from the first compartment into the surrounding environment;

the at least a first compartment including a first connector to establish a fluid connection with the hazardous pharmaceutical vessel; and

at least a first outlet in fluid connection with the first connector.

2. The assembly of claim 1 further including at least a second compartment adapted to contain a fluid other than the hazardous pharmaceutical, the second compartment being in fluid connection with the first outlet.

3. A container comprising a flexible sealing member that cooperates with a connector to create a biohazard seal during connection of the container to the connector.

4. The container of claim 3 wherein the flexible sealing member is circumferential.

5. The container of claim 3 where in the flexible sealing member is axially compressed during connection.

6. A connector comprising a first member and a second member, at least one of the first member or the second member comprising a biohazard seal adapted to contain biohazardous material during connection of the first member and the second member.

7. A container for a biohazardous material, the container including a first septum sealing a port into the container and a second septum sealing the port, the second septum being spaced from the first septum.

8. A system for delivering a hazardous fluid to a patient comprising:

a container suitable for holding a hazardous fluid and comprising a hazardous enclosure to shield against harmful effects of the hazardous fluid; and

a pump device capable of pumping the hazardous fluid from the container and delivering the hazardous fluid to the patient;

wherein the container is adapted to be removably attachable to the pump device.

9. The system of claim 8 wherein the hazardous fluid comprises a radiopharmaceutical fluid and the hazardous enclosure is radiation shielded.

10. The system of claim 8 wherein the container comprises a heating/cooling element for heating/cooling the hazardous fluid.

11. The system of claim 8 wherein the container is removably attached to the pump device via a release latch.

12. The system of claim 8 wherein the pump device comprises controls positioned on the body of the pump device to control operation of the pump device.

13. The system of claim 8 further comprising a remote control device associated with the pump device to control operation of the pump device.

14. The system of claim 8 wherein the container is disposable.

15. The system of claim 8 further comprising a second container removably attachable to the pump device and containing a different fluid from the hazardous fluid.

16. The system of claim 15 wherein the hazardous fluid comprises a radiopharmaceutical fluid and the different fluid comprises a diluent fluid.

17. The system of claim 15 further comprising a mixing device associated with the pump device for mixing the hazardous fluid and the different fluid for delivering a fluid mixture of the hazardous fluid and the different fluid to the patient.

18. The system of claim 15 wherein the mixing device comprises a sterile tubing set for mixing the hazardous fluid and the different fluid.