Dosing Operation In A Medical Device

• US 20100185152A1
• Filed: 02/03/2006
• Published: 07/22/2010
• Est. Priority Date: 02/14/2005
• Status: Abandoned Application

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Jensen, Bo Vestergaard, Larsen, Andre
• Application Number:
  US11/814,498
• Publication Number:
  US 20100185152A1
• Time in Patent Office: Days
• US Class Current: 604/154
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2005/31588 electrically driven
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/31573 Accuracy improving means

Abstract

This invention relates to a method of controlling a dosing operation where a piston in a medical device is moved to a desired position, the dosing operation applies a motor to provide a force from the piston to expel a dose of a liquid medicament, said method comprising the steps of: moving the piston, at a first fixed speed, to a first position of the movement, moving the piston, at a decreasing speed, from said first position to a second position of the movement, and moving the piston, at a second fixed speed, from said second position to the desired position of the movement. The method further comprises the step of letting a fixed waiting time pass, when the piston has reached the desired position. This enables for a precise movement and stop of the piston leading to a precise dose, minimized post dripping and to that only a fixed and short waiting time need to go before a user can withdraw an injection needle of the medical device from his skin.

Claims

1. A method of controlling a dosing operation where a piston in a medical device is moved to a desired position of movement, the dosing operation applies a motor to provide a force from the piston to expel a dose of a liquid medicament, said method comprising:

moving the piston, at a first fixed speed, to a first position of the movement,

moving the piston, at a decreasing speed, from said first position to a second position of the movement, and moving the piston, at a second fixed speed, from said second position to the desired position S_ref.

2. The method according to claim 1, further comprising letting a fixed waiting time pass when the piston has reached the desired position.

3. The method according to claim 1, wherein said first position referred to as RampOnset and is calculated as Fdose_avg/Fmin*Min_{Ramp distance}, where Fdose_avg is the average dosing force during movement at said first fixed speed, Fmin is the minimum allowable average dosing force, and Min_{Ramp distance} is the minimum ramp onset position.

4. The method according to claim 1, wherein said second position is reached when said decreasing speed hits v_Min, the minimum speed of said motor, thereby ensuring that said motor does not run at a lower speed than said minimum speed.

5. The method according to claim 1, wherein said first fixed speed is a nominal dosing speed, V_TargetSpeed.

6. The method according to claim 3, wherein said decreasing speed V_rampdown is calculated as

$V_{\mathrm{rampdown}}=\frac{S_{\mathrm{ref}}-S}{\mathrm{RampOnset}}·$

V TargetSpeed ,

S_ref is the desired position, V_TargetSpeed is the nominal dosing speed, and S is the current position of said movement from said first position to said second position.

7. The method according to claim 6, wherein said second fixed speed is V_Min, the minimum speed of said motor.

8. The method according to claim 1, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.

9. The method according to claim 1, wherein said fixed waiting time is selected as a fixed number from an interval between 2 to 6 seconds.

10. The method according to claim 9, wherein the fixed waiting time is set to about 2 seconds.

11. The method according to claim 9, wherein the fixed waiting time is set to about 3 seconds.

12. The method according to claim 9, wherein the fixed waiting time is set to about 4 seconds.

13. The method according to claim 9, wherein the fixed waiting time is set to about 5 seconds.

14. The method according to claim 2, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.

15. The method according to claim 3, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.

16. The method according to claim 4, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.

17. The method according to claim 5, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.

18. The method according to claim 6, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.

19. The method according to claim 7, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.

20. The method according to claim 9, wherein said liquid medicament is insulin, GLP-1 or human growth hormone.