SYSTEMS AND METHODS FOR FLUID DELIVERY

• US 20100185175A1
• Filed: 09/15/2009
• Published: 07/22/2010
• Est. Priority Date: 02/09/2006
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Kamen, Dean, Mandro, Marc A., Gray, Larry B., Kerwin, John M., Blumberg, David JR.
• Granted Patent: US 10,010,669 B2
• Time in Patent Office: Days
• US Class Current: 604/504
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2005/16863 Occlusion detection
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 2205/0294 Piezoelectric materials
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3546 Range
• CPC Class Codes: A61M 2205/3576 with non implanted data transmission devices, e.g. using external transmitter or receiver
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/8237 Charging means
• CPC Class Codes: A61M 2206/22 eliminating pulsatile flows, e.g. by the provision of a dampening chamber
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 : of the skin patch type
• CPC Class Codes: A61M 5/14586 : pressurised by means of a flexible diaphragm
• CPC Class Codes: A61M 5/16809 : by repeated filling and emptying of an intermediate volume pressure infusion using positive displacement pumps A61M5/142
• CPC Class Codes: A61M 5/16886 : for measuring fluid flow rate, i.e. flowmeters
• CPC Class Codes: A61M 5/172 : electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G01F 11/086 : using an auxiliary pressure to cooperate with the diaphragm or bellows
• CPC Class Codes: G05D 7/0647 : the plurality of throttling means being arranged in series
• CPC Class Codes: G05D 7/0676 : by action on flow sources G05D7/0688, G05D7/0694 take precedence
• CPC Class Codes: G08C 17/02 : using a radio link
• CPC Class Codes: H04B 7/2609 : Arrangements for range control, e.g. by using remote antennas
• CPC Class Codes: Y10T 29/49236 : Fluid pump or compressor making
• CPC Class Codes: Y10T 29/494 : Fluidic or fluid actuated device making
• CPC Class Codes: Y10T 29/49412 : with assembly, disassembly or composite article making
• CPC Class Codes: Y10T 29/49826 : Assembling or joining
• CPC Class Codes: Y10T 29/49828 : Progressively advancing of work assembly station or assembled portion of work

Abstract

A system for at least partial closed-loop control of a medical condition is disclosed. The system includes at least one medical fluid pump. The medical fluid pump including a sensor for determining the volume of fluid pumped by the pump. Also, at least one continuous analyte monitor, and a controller. The controller is in communication with the medical fluid pump and the at least one continuous analyte monitor. The controller includes a processor. The processor includes instructions for delivery of medical fluid based at least on data received from the at least one continuous analyte monitor.

Claims

1. A system for at least partial closed-loop control of a medical condition, the system comprising:

at least one medical fluid pump, the medical fluid pump comprising a sensor for determining the volume of fluid pumped by the pump;

at least one continuous analyte monitor; and

a controller, the controller in communication with the medical fluid pump and the at least one continuous analyte monitor, the controller comprising a processor, the processor comprising instructions for delivery of medical fluid based at least on data received from the at least one continuous analyte monitor.

2. The system of claim 1 wherein the sensor further comprising an acoustic volume sensor.

3. The system of claim 1 further comprising a network operation center, the network operation center in communication with the processor.

4. The system of claim 1 wherein the pump further comprising:

a pumping chamber having an inlet connectable to provide fluid communication with a fluid source, and a pump outlet; and

a force application assembly adapted to provide a compressive stroke to the pumping chamber,

wherein the compressive stroke causes a restriction of retrograde flow of fluid from the pumping chamber through the inlet while urging fluid from the pumping chamber to the pump outlet.

5. The system of claim 4 further comprising wherein the force application assembly is coupled to an inlet valve actuator and to a pump actuator, so that the compressive stroke actuates an inlet valve coupled between the inlet and the fluid source to close the valve when the pump actuator causes fluid to be urged from the pumping chamber to the pump outlet.

6. The system of claim 5 further comprising wherein the force application assembly comprising a motor for coordinated operation of the valve actuator and the pump actuator, wherein the motor includes at least one shape-memory actuator.

7. The system of claim 1 wherein at least one of the continuous analyte monitors is a continuous glucose monitor.

8. The system of claim 1 further comprising at least one accelerometer.

9. The system of claim 1 further comprising at least one blood oxygen sensor.

10. The system of claim 1 further comprising at least one inertial measurement unit comprising at least one accelerometer and at least one gyroscope.

11. The system of claim 1 further comprising at least one temperature sensor.

12. A method for at least partial closed-loop control of a medical condition, the method comprising:

receiving glucose data during a time frame or an event;

comparing the glucose data to a previous and similar time frame or event;

determining an unexpected result during the time frame or the event; and

sending an alert signal to indicate an unexpected result.

13. The method of claim 12 further comprising wherein sending an alert signal comprising alerting a user of the unexpected result.

14. The method of claim 13 further comprising prompting the user to enter information regarding the unexpected result.

15. The method of claim 14 further comprising wherein the system not receiving information regarding the unexpected result from the user, shutting down the system.

16. The method of claim 15 further comprising wherein shutting down the system comprising alerting the user of the shutdown through a series of alarms.

17. The method of claim 16 further comprising wherein alerting the user of the shutdown through a series of alarms comprising alerting the user of the shutdown through a series of increasing alarms.

18. A method for at least partial closed-loop control of a medical condition, the method comprising:

receiving medical fluid delivery data during a time frame or an event;

comparing the medical fluid delivery data to a previous and similar time frame or event;

determining an unexpected result during the time frame or the event; and

sending an alert signal to indicate an unexpected result.

19. The method of claim 18 further comprising wherein sending an alert signal comprising alerting a user of the unexpected result.

20. The method of claim 19 further comprising prompting the user to enter information regarding the unexpected result.

21. The method of claim 20 further comprising wherein the system not receiving information regarding the unexpected result from the user, shutting down the system.

22. The method of claim 21 further comprising wherein shutting down the system comprising alerting the user of the shutdown through a series of alarms.

23. The method of claim 22 further comprising wherein alerting the user of the shutdown through a series of alarms comprising alerting the user of the shutdown through a series of increasing alarms.

24. A method for monitoring the integrity of an analyte sensor, the method comprising:

injecting a volume of an analyte having a predetermined concentration in close proximity to a continuous analyte sensor for the analyte;

receiving data from the continuous analyte sensor; and

analyzing the data to determine whether the analyte sensor is responsive to the injected volume of analyte.

25. The method of claim 24 further comprising wherein the analyte is glucose.