Sensor having integrated electrodes and method for detecting analytes in fluids

• US 20100188110A1
• Filed: 03/24/2010
• Published: 07/29/2010
• Est. Priority Date: 09/09/2002
• Status: Active Grant

• Current Assignee: Yizhong Sun
• Original Assignee: Yizhong Sun
• Inventors: Sun, Yizhong
• Granted Patent: US 8,519,726 B2
• Time in Patent Office: Days
• US Class Current: 324/694
• CPC Class Codes: G01N 33/0031 comprising two or more sensors, e.g. a sensor array
• CPC Class Codes: G01N 33/0034 comprising neural networks or related mathematical techniques

Abstract

A sensor having integrated electrodes in a single sensor configuration, which is operated by alternating current (AC) including periodic electrical excitation signals of the respective multiple frequencies with the same amplitude for detecting analytes in fluids. The sensor applies a total of an odd number of the identical conductors serving as the respective electrodes, which are positioned equally spaced apart, in order, alignment and parallel with each other. The odd numbered conductors of the total conductors are connected in parallel by a first electrically conducting means serving as a first electrical pole to form a first group of the integrated electrodes. The even numbered conductors are connected in parallel by a second electrically conducting means serving as a second electrical pole to form a second group of the integrated electrodes. The present invention sensor possesses properties of high output, reduced physical size and improved electrical characteristics.

Claims

1. A sensor, comprising:

a. an analytical sensor including first, second and third identical electrodes, which are positioned equally spaced apart in order, alignment and parallel with each other, wherein said first and third electrodes are electrically connected in parallel by a first electrically conducting means serving as a first electrical pole and said second electrode is connected by a second electrically conducting means serving as a second electrical pole, said first and second electrodes are electrically separated by a first non-conductive material and said second and third electrode are electrically separated by a second non-conductive material that is identical to said first non-conductive material;

b. said analytical sensor is brought into contact with a first fluid containing an analyte;

c. said first and second electrical poles of said analytical sensor are electrically connected to an alternating current (AC) analyzing device, wherein said AC analyzing device applies various frequencies of AC signals to said analytical sensor;

d. AC related electrical properties are detected for said analytical sensor when contacted by said first fluid containing said analyte according to said applied various frequencies of said AC signals, wherein said electrical properties are detected at each of said applied various frequencies; and

e. said detected AC related electrical properties according to a selected subgroup of said applied various frequencies are used for identification of said analyte.

2. The sensor as claimed in claim 1, wherein said AC related electrical properties include impedance, resistance, reactance, phase angle, voltage and current.

3. The sensor as claimed in claim 1, further comprising a first conductive material that is positioned between said first and second electrodes of said analytical sensor, and a second conductive material that is positioned between said second and third electrodes, wherein said first and second conductive materials are identical.

4. The sensor as claimed in claim 1, wherein said non-conductive material positioned between said electrodes is selected from the group consisting of polymer, polymer inorganic material composite, molecular sieves, particles of the respective silica gel, alumina, porous carbon, calcium carbonate and fluorocarbon, liquid organic salts, composite of one of platinum group of metals composited by filler consisting of inorganic or organic materials, polymer modified porous ceramic particles, polymer modified fluorocarbon particles, polymer modified porous silica, and polymer modified porous glass beads.

5. The sensor as claimed in claim 4, further comprising said electrodes of said analytical sensor that are spatial electrodes, or thick film electrodes having a ceramic substrate, or thin film electrodes having a silicon substrate, wherein surface treatment reagents are used to treat surfaces of the respective ceramic substrate, silicon substrate, and particles of the respective silica gel, alumina, porous carbon and fluorocarbon.

6. The sensor as claimed in claim 1, said analytical sensor further includes a total of an odd number of the identical conductors serving as the respective electrodes that are positioned equally spaced apart, in order, alignment and parallel with each other, wherein odd numbered electrodes from said total electrodes are connected in parallel by a first electrically conducting means serving as a first electrical pole to form a first group of integrated electrodes, and odd number electrodes are connected in parallel by a second electrically conducting means serving as a second electrical pole to form a second group of integrated electrodes.

7. The sensor as claimed in claim 1, further comprising means for implementing a temperature programming technique to said analytical sensor.

8. The sensor as claimed in claim 1, further comprising:

a. said analytical sensor is brought into contact with a second fluid which is identical to said first fluid but does not contain any analyte;

b. AC related electrical properties are detected for said analytical sensor when contacted by said second fluid according to said applied various frequencies of said AC signals, wherein said electrical properties are detected at each of said applied various frequencies;

c. combined AC related electrical properties of said analyte are obtained by combining the respective AC related electrical properties of said analytical sensor when contacted by said first fluid containing said analyte with the respective AC related electrical properties of said analytical sensor when contacted by said second fluid, and

d. said combined AC related electrical properties according to a selected subgroup of said applied various frequencies are used for identification of said analyte.

9. The sensor as claimed in claim 1, further comprising an odorant as said analyte.

10. The sensor as claimed in claim 1, wherein said analyte is selected from studies of materials containing illegal substances, environment concerns, medical interests including hospital concerns, scientific and research interests including space research interests, interests of industrial sectors including food, beverages, agricultural, chemical, petroleum, plastic, construction, pharmaceutical automobile, biochemical, and transportation, consumer interests including perfume, cosmetic, wine and flavor, and safety concerns including explosive, arson and road spill investigation.

11. The sensor as claimed in claim 1, further comprising a reference sensor that is identical to said analytical sensor, wherein said reference sensor is used for correcting background subjects and selectively detecting known biochemical marker or biochemical markers.

12. The sensor as claimed in claim 1, further comprising at least two said analytical sensor.

13. A sensor, comprising:

a. an analytical sensor including first, second and third identical electrodes, which are positioned equally spaced apart in order, alignment and parallel with each other, wherein said first and third electrodes are electrically connected in parallel by a first conducting means serving as a first electrical pole and said second electrode is connected by a second conducting means serving as a second electrical pole, said first and second electrodes are electrically separated by a first non-conductive material and said second and third electrode electrically separated by a second non-conductive material that is identical to said first non-conductive material;

b. said analytical sensor is brought into contact with a first fluid containing an analyte;

c. said first and second electrical poles of said analytical sensor are electrically connected to an alternating current (AC) analyzing device, wherein said AC analyzing device applies a frequency of an AC signal to said analytical sensor;

d. AC related electrical properties are detected for said analytical sensor when contacted by said first fluid containing said analyte according to said applied frequency of said AC signal; and

e. one of said detected AC related electrical properties is used for detection of said analyte.

14. The sensor as claimed in claim 13, wherein said AC related electrical properties include impedance, resistance, reactance, and phase angle.

15. The sensor as claimed in claim 13, wherein said non-conductive material positioned between said electrodes is selected from the group consisting of polymer, polymer inorganic material composite, molecular sieves, particles of the respective silica gel, alumina, porous carbon, calcium carbonate and fluorocarbon, liquid organic salts, composite of one of platinum group of metals composited by filler consisting of inorganic or organic materials, polymer modified porous ceramic particles, polymer modified fluorocarbon particles, polymer modified porous silica, and polymer modified porous glass beads.

16. The sensor as claimed in claim 13, further comprising a first conductive material that is positioned between said first and second electrodes of said analytical sensor, and a second conductive material that is positioned between said second and third electrodes, wherein said first and second conductive materials are identical.

17. The system as claimed in claim 13, wherein said analyte is selected from studies of materials containing illegal substances, environment concerns, medical interests including hospital concerns, scientific and research interests including space research interests, interests of industrial sectors including food, beverages, agricultural, chemical, petroleum, plastic, construction, pharmaceutical automobile, biochemical, and transportation, consumer interests including perfume, cosmetic, wine and flavor, and safety concerns including explosive, arson and road spill investigation.

18. The sensor as claimed in claim 13, further comprising said electrodes of said analytical sensor that are spatial electrodes, or thick film electrodes having a ceramic substrate, or thin film electrodes having a silicon substrate, wherein surface treatment reagents are used to treat surfaces of the respective ceramic substrate, silicon substrate, and particles of the respective silica gel, alumina, porous carbon and fluorocarbon.

19. The sensor as claimed in claim 18, said analytical sensor further includes a total of an odd number of the identical conductors serving as the respective electrodes that are positioned equally spaced apart, in order, alignment and parallel with each other, wherein odd numbered electrodes from said total electrodes are connected in parallel by a first electrically conducing means serving as a first electrical pole to form a first group of integrated electrodes, and even number electrodes are connected in parallel by a second conducting means serving as a second electrical pole to form a second group of integrated electrodes.

20. A sensor, comprising:

a. an analytical sensor comprising first, second and third identical electrodes, which are positioned equally spaced apart in order, alignment and parallel with each other, wherein said first and third electrodes are electrically connected in parallel by a first electrically conducting means serving as a first electrical pole and said second electrode is connected by a second electrically conducting means serving as a second electrical pole, said first and second electrodes are electrically separated by a first non-conductive material and said second and third electrode are electrically separated by a second non-conductive material that is identical to said first non-conductive material;

b. said analytical sensor is brought into contact with a fluid containing an analyte;

c. means, applied by various frequencies of AC signals, for detecting AC related electrical properties of said analytical sensor when contacted by said fluid containing said analyte according to said applied various frequencies, wherein said electrical properties are detected at each of said applied various frequencies; and

d. said detected AC related electrical properties according to a selected subgroup of said applied various frequencies are used for identification of said analyte.