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System and Method for Correcting Primer Extension Errors in Nucleic Acid Sequence Data

  • US 20100192032A1
  • Filed: 02/15/2007
  • Published: 07/29/2010
  • Est. Priority Date: 02/16/2006
  • Status: Active Grant
First Claim
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1. A method for correcting an error associated with phasic synchrony of sequence data generated from a population of substantially identical copies of a template molecule, comprising:

  • (a) detecting a signal generated in response to an incorporation of one or more nucleotides in a sequencing reaction;

    (b) generating a value for the signal; and

    (c) correcting the value for the phasic synchrony error using a first parameter and a second parameter.

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