METHOD, APPARATUS AND SYSTEM FOR DETECTION OF ARTERIAL STIFFNESS AND ARTERY TONUS BY PULSE CURVE GEOMETRY ANALYSIS

• US 20100198088A1
• Filed: 05/01/2008
• Published: 08/05/2010
• Est. Priority Date: 05/01/2007
• Status: Abandoned Application

• Current Assignee: Spirocor Ltd.
• Original Assignee: Spirocor Ltd.
• Inventors: Tal, Yoram, Arbel, Ronen, Ortenberg, Michael
• Application Number:
  US12/598,181
• Publication Number:
  US 20100198088A1
• Time in Patent Office: Days
• US Class Current: 600/501
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives

Abstract

System and method for determining a condition of a cardiovascular system are provided. One or more pulse curves may be obtained. At least two points on the pulse curve, substantially including a dicrotic notch may be selected. A first parameter pertaining to a section of the pulse curve contained by the selected points may be calculated. A second parameter pertaining to a curve other than the pulse curve and traversing the selected points may be calculated. A notch coefficient may be computed by relating the first parameter to the second parameter. Other embodiments are described and claimed.

Claims

1. A method for detecting a condition of a cardiovascular system comprising:

obtaining a pulse curve related to said cardiovascular system;

locating two edge points of a dicrotic wave associated with said pulse curve;

determining a first parameter pertaining to a section of said pulse curve wherein said section is delimited by said two edge points;

determining a second parameter pertaining to a line connecting said two edge points;

calculating a notch coefficient parameter by using said first parameter and said second parameter; and

utilizing said notch coefficient parameter as an indicator of said condition.

2. The method of claim 1, wherein said line is a straight line.

3. The method of claim 1, wherein said first parameter is a length of said section of said pulse curve and wherein said second parameter is a length of said line.

4. The method of claim 1, wherein calculating said notch coefficient parameter comprises dividing said first parameter by said second parameter.

5. The method of claim 1, wherein utilizing said notch coefficient parameter comprises determining the condition of the cardiovascular system by comparing said notch coefficient parameter to a predefined threshold.

6. The method of claim 1, wherein said condition is an arterial stiffness.

7. The method of claim 1, wherein said condition is an artery tonus condition.

8. The method of claim 1, calculating the notch coefficient parameter comprises calculating e^(L1/L2)−

e, wherein L1 is a length of said section of said pulse curve and wherein L2 is a length of said line.

9. The method of claim 1, wherein obtaining the pulse curve comprises utilizing a photoplethysmograph (PTG) measuring device.

10. An article comprising a computer-storage medium having stored thereon instructions that, when executed by a processing platform, result in:

obtaining a pulse curve related to a cardiovascular system;

locating two edge points of a dicrotic wave associated with said pulse curve;

determining a first parameter pertaining to a section of said pulse curve wherein said section is delimited by said two edge points;

determining a second parameter pertaining to a line connecting said two edge points;

calculating a notch coefficient parameter by using said first parameter and said second parameter; and

utilizing said notch coefficient parameter to compute an indicator of a condition of said cardiovascular system.

11. The article of claim 10, wherein the instructions when executed to calculate the notch coefficient further result in:

calculating said notch coefficient parameter by dividing a length of said section of said pulse curve by a length of said line.

12. The article of claim 10, wherein the instructions when executed further result in comparing said notch coefficient parameter to a predefined threshold;

and determining the condition of the cardiovascular system.

13. A system comprising:

a sensor to obtain a volumetric measurement related to a cardiovascular system of a subject;

an interface module to convert information received from said sensor;

a computing device to receive the information from said interface module and to calculate a notch coefficient based on said information by;

obtaining a pulse curve related to the cardiovascular system;

locating two edge points of a dicrotic wave associated with said pulse curve;

determining a first parameter pertaining to a section of said pulse curve wherein said section is delimited by said two edge points;

determining a second parameter pertaining to a line connecting said two edge points;

calculating a notch coefficient parameter by using said first parameter and said second parameter; and

utilizing said notch coefficient parameter as an indicator of said condition.

14. The system of claim 13, wherein said computing device to calculate the notch coefficient parameter by dividing a length of said section of said pulse curve by a length of said line.

15. The system of claim 13, wherein said computing device is further to compare said notch coefficient parameter to a predefined threshold and to determine the condition of the cardiovascular system based on said comparing.

16. The system of claim 13, wherein said computing device is to calculate the notch coefficient parameter by calculating e^(L1/L2)−

e, wherein L1 is a length of said section of said pulse curve and wherein L2 is a length of said line.