DEVICE FOR PACKAGING AND SUBLINGUAL ADMINISTRATION OF ACTIVE PRINCIPLES

• US 20100198147A1
• Filed: 07/18/2008
• Published: 08/05/2010
• Est. Priority Date: 07/20/2007
• Status: Active Grant

• Current Assignee: Philippe Perovitch
• Original Assignee: Philippe Perovitch
• Inventors: Perovitch, Philippe
• Granted Patent: US 8,376,988 B2
• Time in Patent Office: Days
• US Class Current: 604/77
• CPC Class Codes: A61J 1/067 Flexible ampoules, the contents of which are expelled by squeezing
• CPC Class Codes: A61J 1/1418 Threaded type
• CPC Class Codes: A61J 1/1468 Containers characterised by specific material properties
• CPC Class Codes: A61J 1/18 Arrangements for indicating condition of container contents, e.g. sterile condition
• CPC Class Codes: A61J 7/0046 Cups, bottles or bags
• CPC Class Codes: B65D 2251/0025 of the 47-type
• CPC Class Codes: B65D 2251/0096 integral with the container
• CPC Class Codes: B65D 47/38 with piercing means arranged to act subsequently as a valve to control the opening
• CPC Class Codes: B65D 51/227 and further comprising a device first inhibiting displacement of the piercing or cutting means

Abstract

The invention provides a container for preparing and/or administering a very small volume of active principles in liquid form, the container comprising a head (12) suitable for taking up a conservation, first position P1 in which said head (12) is in a distal position relative to the container, and an administration, second position P2 in which said head (12) is in a proximal position relative to the container, said head (12) including a cannula (14) with at least one flow channel (16), its length being adapted so that the free end of the flow channel (16) can enable delivery by sublingual and/or paragingival permeation, while the container is being held in the hand.

Claims

1. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, the container comprising a head (12) suitable for taking up a conservation, first position P1 in which said head (12) is in a distal position relative to the container (10), and an administration, second position P2 in which said head (12) is in a proximal position relative to the container (10), said head (12) including a cannula (14) with at least one flow channel (16), its length being adapted so that the free end of the flow channel (16) can enable delivery by sublingual and/or paragingival permeation, while the container is being held in the hand.

2. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that it includes movement means (26) for moving the head (12) in translation, these means comprising an assembly of a screw thread (30) carried by said container (10) and tapping (34) of profile complementary to the screw thread of the container and carried by the head (12) so as to co-operate by screw fastening.

3. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that it includes safety locking means (28) to prevent any unwanted movement in translation of the head (12) relative to the container (10).

4. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 3, the container being characterized in that the locking means (28) comprise a removable ring (36) interposed between the head (12) in the distal position and the container (10).

5. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that the cannula (14) is provided with a mouthpiece cover (22) for safety purposes that can be broken off.

6. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that it includes a neck (32) and in that the opening of the neck is provided with a leakproof capsule (40).

7. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that it includes at least two compartments (52), each compartment being separated by a leakproof capsule (54).

8. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 7, the container being characterized in that each compartment (52) contains at least an active principle, an excipient, an antigen substance, and/or a solvent.

9. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 6, the container being characterized in that it includes perforation means (24) for perforating the capsule(s) (40 and/or 54).

10. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 9, the container being characterized in that the perforation means (24) are disposed at the root of the cannula (14).

11. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 7, the container being characterized in that the perforation means (24) are disposed at the root of the cannula (14) and/or in contiguity with compartments (52) so as to enable the substances contained in said compartments to be mixed together in a determined order.

12. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that the head (12) includes an active principle, an antigen substance, an excipient, and/or a solvent.

13. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that it includes a gripper blade (46) located at the bottom portion of the body of the container (10) so as to enable it to be gripped securely between two fingers.

14. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that the head (12) includes gripper means (48) on its peripheral outside surface.

15. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 1, the container being characterized in that it is suitable for administering active principles and/or antigen substances for the purposes of pharmaceutical, homeopathic, and/or allergy desensitization treatments.

16. A container (10) for preparing and/or administering a very small volume of active principles in liquid form, according to claim 15, the container being characterized in that it is adapted for mucosal administration.