LOCAL DELIVERY OF WATER-SOLUBLE OR WATER-INSOLUBLE THERAPEUTIC AGENTS TO THE SURFACE OF BODY LUMENS
First Claim
1. A catheter assembly for insertion into the vasculature comprising:
- an expandable structure having an outer surface;
a non-durable coating complexed with iodine disposed on the outer surface of the expandable structure; and
a substantially water-insoluble therapeutic agent dispersed in the non-durable coating.
13 Assignments
0 Petitions
Accused Products
Abstract
A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which is complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.
-
Citations
20 Claims
-
1. A catheter assembly for insertion into the vasculature comprising:
-
an expandable structure having an outer surface; a non-durable coating complexed with iodine disposed on the outer surface of the expandable structure; and a substantially water-insoluble therapeutic agent dispersed in the non-durable coating. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. A method of delivering a substantially water-insoluble therapeutic agent to a vascular lumen comprising:
-
providing a catheter assembly having a non-durable coating disposed on an outer surface of an expandable structure of the catheter assembly, wherein the non-durable coating is complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein; introducing said catheter assembly into a vascular lumen; expanding said expandable structure of said catheter assembly to contact said coating against said vascular lumen; and contracting said expandable structure. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
-
Specification