MOTION CORRECTION IN NUCLEAR IMAGING

• US 20100202664A1
• Filed: 07/11/2008
• Published: 08/12/2010
• Est. Priority Date: 07/26/2007
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Inventors: Busch, Marc, Brinks, Ralph
• Granted Patent: US 8,351,671 B2
• Time in Patent Office: Days
• US Class Current: 382/107
• CPC Class Codes: A61B 6/037 Emission tomography
• CPC Class Codes: G06T 11/005 Specific pre-processing for tomographic reconstruction, e.g. calibration, source positioning, rebinning, scatter correction, retrospective gating
• CPC Class Codes: G06T 2211/412 Dynamic

Abstract

A radiation detection apparatus (100) acquires projection data of an object that is subject to motion during the acquisition. The apparatus includes a motion modeler (142) and a motion compensator (142) that cooperate to compensate for a motion of the object during the acquisition. In one example, the projection data includes list mode positron emission tomography data and the apparatus compensates for cardiac motion.

Claims

1. An apparatus comprising:

a motion modeler that models, in a first projection of projection data indicative of radionuclide decays in an object, a motion of the object;

a motion compensator that uses the modeled motion to apply a spatial correction to projection data of the projection.

2. The apparatus of claim 1 wherein the motion modeler models, in a plurality of projections of projection data indicative of radionuclide decays in the object, a motion of the object.

3. The apparatus of claim 1 wherein the motion modeler models a time-varying spatial characteristic of projection data of the projection.

4. The apparatus of claim 3 wherein the characteristic includes the location of a center of the projection data.

5. The apparatus of claim 1 wherein the motion modeler generates a time-varying spatial displacement vector and the motion compensator uses the displacement vector to compensate for a motion of the object.

6. The apparatus of claim 1 wherein the motion modeler uses a spatially varying weighting function to compensate for a spatially varying displacement of a feature of the object.

7. The apparatus of claim 6 wherein the motion modeler determines a difference between a first spatial dimension of the projection data of the projection and a second spatial dimension of the projection data and applies the weighting function to the determined difference.

8. The apparatus of claim 1 wherein the projection data includes events indicative of radionuclide decays in the object, the apparatus includes a projection data filter that filters the projection data to select events indicative of radionuclide decays occurring in a sub-region of the object, and the motion modeler uses the filtered data to model the motion of the object.

9. The apparatus of claim 8 wherein the projection data filter weights an event according to one of at least three different weight values as a function of the likelihood that the event is indicative of a radionuclide decay occurring in the sub-region.

10. The apparatus of claim 1 including a projection sorter and a temporal sorter that sort the projection data into a plurality of projections and temporal groups.

11. The apparatus of claim 1 including a histogram generator that generates a histogram of projection data of the projection.

12. The apparatus of claim 11 wherein the projection data of the projection includes projection data indicative of radionuclide decays occurring at first and second times during an examination of the object and the histogram generator generates a first histogram of projection data indicative of radionuclide decays occurring at the first time and a second histogram of projection data indicative of radionuclide decays occurring at the second time.

13. The apparatus of claim 11 including a projection motion determiner that uses the histogram to determine a motion of the object.

14. The apparatus of claim 1 wherein the apparatus forms part of a positron emission tomography detector.

15. The apparatus of claim 14 wherein the apparatus forms part of a system that includes a positron emission tomography scanner and a second modality scanner.

16. A method of compensating for a motion of an object, the method comprising:

modeling, in a first projection of projection data indicative of radionuclide decays in the object, a motion of the object;

using the modeled motion to apply a spatial correction to projection data of the first projection.

17. The method of claim 16 including:

modeling, in a second projection of the projection data, a motion of the object;

using the motion modeled in the second projection to apply a spatial correction to projection data of the second projection.

18. The method of claim 16 including:

using projection data of the first projection to model a first distribution of a radionuclide in the object at a first time during an examination of the object;

using projection data of the first projection to model a second distribution of a radionuclide in the object at a second time during an examination of the object.

19. The method of claim 18 including:

modeling a time-varying spatial characteristic of the first and second distributions;

determining a variation between a value of the modeled time-varying spatial characteristic and a second value;

using the determined variation to generate a time-varying displacement vector.

20. The method of claim 19 wherein the method includes weighting the determined variation according to a spatially varying weighting function and the step of using the determined variation includes using the weighted determined variation to generate a time- and spatially-varying displacement vector.

21. The method of claim 19 wherein the second value includes an average value of the modeled characteristic.

22. The method of claim 16 wherein the projection data includes projection data indicative of a beating heart and using includes using the modeled motion to compensate for a motion induced by a contraction of the heart.

23. A computer readable storage medium including instructions which, when executed by a computer, cause the computer to carry out the method of claim 16.

24. A motion compensation method comprising:

determining an object motion-induced temporal variation of a spatial characteristic of projection data acquired in an examination of the object, wherein the projection data is indicative of radionuclide decays in the object;

using the determined temporal variation to correct the projection data.

25. The method of claim 24 wherein the spatial characteristic includes at least one of a location or a dimension of a projection of the projection data on a projection surface.

26. The method of claim 25 wherein spatial characteristic includes a dimension and the method includes compensating for a spatially non-uniform temporal variation the dimension of the projection of the data on the surface.

27. The method of claim 24 wherein determining includes determining the temporal variation of the spatial characteristic in each of a plurality of projections of the projection data and using includes the determined variations to correct the projection data of the projections.

28. The method of claim 24 wherein the projection data includes list mode time of flight positron emission data and the method includes:

filtering the projection data to select projection data indicative of positron annihilations occurring in a sub-region of the object;

sorting the projection data into a plurality of projections and temporal groups;

for each of a plurality of projections and temporal groups, generating a histogram indicative of a spatial distribution of positron emissions in the object;

using the histograms to model a motion of the object.

29. The method of claim 28 wherein using the histograms includes using the histograms to model a motion of the object in three spatial dimensions.

30. The method of claim 24 including:

using the motion corrected projection data to generate image space data;

presenting information indicative of the image space data in human perceptible form.