Detection of Vascular Conditions Using Arterial Pressure Waveform Data
First Claim
1. A model for use in detecting a vascular condition in a subject comprising:
- a multivariate statistical model based on arterial pressure waveform data from a first group of subjects that were experiencing the vascular condition and a second group of subjects that were not experiencing the vascular condition, the multivariate statistical model providing a model output value that corresponds to a first established value for the arterial pressure waveforms of the first set of arterial pressure waveform data and a second established value for the arterial pressure waveforms of the second set of arterial pressure waveform data.
1 Assignment
0 Petitions
Accused Products
Abstract
Multivariate statistical models for the detection of vascular conditions, methods for creating such multivariate statistical models, and methods for the detection of vascular condition in a subject using the multivariate statistical models are described. The models are created based on arterial pressure waveform data from a first group of subjects that were experiencing a particular vascular condition and a second group of subjects that were not experiencing the same vascular condition. The multivariate statistical models are set up to provide different output values for each set of input data. Thus, when data from a subject under observation is input into the model, the relationship of the model output value to the established output values for the two groups upon which the model was established will indicate whether the subject is experiencing the vascular condition.
-
Citations
32 Claims
-
1. A model for use in detecting a vascular condition in a subject comprising:
a multivariate statistical model based on arterial pressure waveform data from a first group of subjects that were experiencing the vascular condition and a second group of subjects that were not experiencing the vascular condition, the multivariate statistical model providing a model output value that corresponds to a first established value for the arterial pressure waveforms of the first set of arterial pressure waveform data and a second established value for the arterial pressure waveforms of the second set of arterial pressure waveform data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
-
9. A method for creating a model for use in detecting a vascular condition in a subject comprising:
-
providing a first set of arterial pressure waveform data from a first group of subjects that were experiencing the vascular condition; providing a second set of arterial pressure waveform data from a second group of subjects that were not experiencing the vascular condition; and building a multivariate statistical model based on the first and second sets of arterial pressure waveform data, the multivariate statistical model providing a model output value that corresponds to a first established value for the arterial pressure waveforms of the first set of arterial pressure waveform data and a second established value for the arterial pressure waveform of the second set of arterial pressure waveform data. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17)
-
-
18. A method for detecting a vascular condition in a subject comprising:
-
providing arterial pressure waveform data from the subject; applying a multivariate statistical model to the arterial pressure waveform data to determine a cardiovascular parameter, the multivariate statistical model being prepared from a first set of arterial pressure waveform data from a first group of subjects that were experiencing the vascular condition and a second set of arterial pressure waveform data from a second group of subjects that were not experiencing the vascular condition, the multivariate statistical model providing a cardiovascular parameter that corresponds to a first established value for the arterial pressure waveforms of the first set of arterial pressure waveform data and a second established value for the arterial pressure waveform of the second set of arterial pressure waveform data; and comparing the cardiovascular parameter to a threshold value, wherein a cardiovascular parameter equal to or greater than the threshold value indicates the subject is experiencing the vascular condition, and a cardiovascular parameter less than the threshold value indicates the subject is not experiencing the vascular condition. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
-
Specification