DELIVERY SYSTEM CARTRIDGE

• US 20100204699A1
• Filed: 02/12/2010
• Published: 08/12/2010
• Est. Priority Date: 02/12/2009
• Status: Active Grant

• Current Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Original Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Inventors: Wei, Guobao, Boyce, Todd M., Shimp, Lawrence A.
• Granted Patent: US 9,011,537 B2
• Time in Patent Office: Days
• US Class Current: 606/76
• CPC Class Codes: A61B 17/823 for the sternum
• CPC Class Codes: A61B 17/8819 characterised by the introducer proximal part, e.g. cannula handle, or by parts which are inserted inside each other, e.g. stylet and cannula A61B17/8825 takes precedence
• CPC Class Codes: A61B 17/8825 characterised by syringe details A61B17/8822, A61B17/8827 take precedence
• CPC Class Codes: A61B 2017/8813 Discharging means for excessively introduced fluid fillers, e.g. discharging excess cement
• CPC Class Codes: A61F 2/30 Joints
• CPC Class Codes: A61F 2/4603 for insertion or extraction of endoprosthetic joints or of accessories thereof
• CPC Class Codes: A61F 2002/0086 for preferentially controlling or promoting the growth of specific types of cells or tissues
• CPC Class Codes: A61F 2002/2825 Femur
• CPC Class Codes: A61F 2002/2835 Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
• CPC Class Codes: A61F 2002/30059 differing in bone mineralization, e.g. made from both mineralized and demineralized adjacent parts
• CPC Class Codes: A61F 2002/30064 Coating or prosthesis-covering structure made of biodegradable material
• CPC Class Codes: A61F 2002/3007 Coating or prosthesis-covering structure made of elastic material, e.g. of elastomer
• CPC Class Codes: A61F 2002/30072 Coating made of plastically deformable or self-moulding material
• CPC Class Codes: A61F 2002/30588 filled with solid particles
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2002/3068 the pharmaceutical product being in a reservoir
• CPC Class Codes: A61F 2002/3093 for promoting ingrowth of bone tissue
• CPC Class Codes: A61F 2002/30971 Laminates, i.e. layered products
• CPC Class Codes: A61F 2002/4627 with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir
• CPC Class Codes: A61F 2310/00592 : Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
• CPC Class Codes: A61F 2310/00958 : Coating or prosthesis-covering structure made of bone or of bony tissue
• CPC Class Codes: A61F 2310/0097 : Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
• CPC Class Codes: A61P 19/04 : for non-specific disorders of the connective tissue
• CPC Class Codes: A61P 43/00 : Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. In some embodiments, the covering may be configured and sized for receipt by an implant device. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust the release of the substance.

Claims

1. A delivery system comprising at least one cartridge configured to be at least partially disposed within at least one containment area of a cage;

said cartridge comprising a covering material containing a bone repair substance configured to allow transfer of the substance or of surrounding materials, actively or passively, upon implantation.

2. A delivery system according to claim 1, further comprising a cage defining said at least one containment area, said cage comprising at least one opening for accessing the containment area said at least one cartridge at least partially disposed within said at least one containment area.

3. The delivery system of claim 2, wherein the cage is configured as a medical implant.

4. The delivery system of claim 3, wherein the implant is an interbody fusion device.

5. The delivery system of claim 3, wherein the implant is a hip stem.

6. The delivery system of claim 3, wherein the implant is for use in a lumbar interbody fusion procedure.

7. The delivery system of claim 2, wherein the cage is formed from one or more of the group consisting of metal, polymer, polyether-etherketone, biocomposite, allograft, xenograft.

8. The delivery system of claim 1, wherein the covering material is resorbable.

9. The delivery system of claim 2, wherein the cartridge is at least partially visible through the cage when the delivery system is configured for implantation.

10. The delivery system of claim 2 wherein the cage is resorbable.

11. The delivery system of claim 2, wherein the cage defines more than one containment area.

12. The delivery system of claim 2, wherein more than one cartridges are at least partially disposed within said at least one containment area.

13. The delivery system of claim 2, wherein the cage defines more than one piece.

14. The delivery system of claim 12, wherein at least one piece is configured to cover the opening.

15. The delivery system of claim 1, wherein the bone repair substance is configured to expand upon implantation.

16. The delivery system of claim 1, wherein the covering material of the cartridge is configured to expand upon implantation.

17. The delivery system of claim 15, wherein the covering material is configured to disintegrate or reabsorb after implantation.

18. A delivery system comprising:

a cylinder-shaped covering material defining a hollow core through said cylinder;

said hollow core positioned defining a radius less than the radius of the cylinder,

the cylinder-shaped covering material defining a compartment with a thickness defined by the radius of the cylinder and the radius of the hollow core, wherein the compartment is configured to retain a bone repair substance.

19. The delivery system of claim 18, for use in a method of delivering bone repair substance to a site of segmental bone reconstruction.

20. The delivery system of claim 18, for use in a method of delivering bone repair substance to a proximal femur revision site.

21. A method of repairing a bone void comprising:

at least partially filling a compartment within a covering material with a bone repair substance;

inserting the covering material into an opening of the defect until the defect is substantially filled;

at least partially removing excess covering material extending beyond the surface of the bone such that the opening of the defect is flush with the uninjured bone surface.

22. The method of claim 21, wherein the defect is the result of vertebroplasty or kyphoplasty.

23. A method of fusing two bones at a bone joint comprising:

creating a first hole in a first bone of a joint;

creating a second hole in a second bone of a joint;

placing one end of a covering material configured to retain a bone repair substance into the first hole;

placing a second end of the covering material into the second hole;

adding a bone repair substance into said covering material; and

allowing two bones at said bone joint to fuse.

24. The method of claim 23, for fusing bones selected from the group containing wrist bones, ankle bones, metatarsals, metacarpals, phalanges.