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METHOD FOR DETERMINING EFFECT OF PREFORMULATION FORMS ON THEIR DISSOLUTION RATES

  • US 20100210027A9
  • Filed: 11/04/2003
  • Published: 08/19/2010
  • Est. Priority Date: 11/04/2002
  • Status: Abandoned Application
First Claim
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1. A method of determining how the solubility of a solid compound-of-interest is affected by its form which comprises:

  • (a) preparing an array of samples, each comprising a controlled amount of the compound-of-interest, wherein the form of the compound-of-interest in at least two of the samples is different;

    (b) forming a liquid portion of each sample by adding a solvent to each sample; and

    (c) determining how much compound-of-interest dissolved in the liquid portion of each sample.

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