Optical System for Imaging of Tissue Lesions

• US 20100210951A1
• Filed: 12/15/2009
• Published: 08/19/2010
• Est. Priority Date: 06/15/2007
• Status: Abandoned Application

• Current Assignee: Rice University, Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Richards-Kortum, Rebecca Rae, Gillenwater, Ann M., Rahman, Mohammed Saidur
• Application Number:
  US12/638,459
• Publication Number:
  US 20100210951A1
• Time in Patent Office: Days
• US Class Current: 600/476
• CPC Class Codes: A61B 5/0071 by measuring fluorescence emission
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/0088 for oral or dental tissue

Abstract

The present disclosure, according to one embodiment, relates to an optical device for direct visualization, imaging, and spectroscopic measurements of tissue abnormalities at various anatomical sites. Such sites include, but are not limited to, the oral cavity, the cervix, and the skin. In one embodiment, the device comprises: a frame; at least one light-emitting diode light source mounted on the frame for illuminating a tissue, wherein the at least one light-emitting diode light source is chosen from a fluorescent light source, a polarized white light source, and an unpolarized white light source; at least one loupe mounted on the frame for visually observing the tissue; at least one filter disposed between the tissue and the loupe for filtering light reflected from the tissue; and an energy source operably connected to the at least one light-emitting diode light source.

Claims

1. A device for examining tissue comprising:

a frame;

at least one light-emitting diode light source mounted on the frame for illuminating a tissue, wherein the at least one light-emitting diode light source is selected from the group consisting of a fluorescent light source, a polarized white light source, and an unpolarized white light source;

at least one loupe mounted on the frame for visually observing the tissue;

at least one filter disposed between the tissue and the loupe for filtering light reflected from the tissue; and

an energy source operably connected to the at least one light-emitting diode light source.

2. The device of claim 1 further comprising a camera mounted on the frame for capturing an image of the tissue and operably connected to the energy source.

3. The device of claim 1 wherein the frame is adapted to be worn on the head of a user.

4. The device of claim 1 wherein the frame is adapted to be held in the hand of a user.

5. The device of claim 1 wherein the camera is a charge-coupled device camera.

6. The device of claim 1 wherein the energy source is a battery.

7. The device of claim 1 wherein the energy source is a lithium-ion battery.

12. The method of claim 10 wherein the tissue is illuminated with a device according to claim 1.

8. A system for visualizing tissue comprising:

a frame;

at least one light-emitting diode light source mounted on the frame for illuminating a tissue, wherein the at least one light-emitting diode light source is selected from the group consisting of a fluorescent light source, a polarized white light source, and an unpolarized white light source;

at least one loupe mounted on the frame for visually observing the tissue;

at least one filter disposed between the tissue and the loupe for filtering light reflected from the tissue;

a camera mounted on the frame for capturing an image of the tissue;

an energy source operably connected to the at least one light-emitting diode light source and the camera; and

a display monitor operably connected to the camera for receiving a signal produced by the camera.

9. The system of claim 8 further comprising a spectrometer operably connected to the camera for measuring the intensity of light reflected from the tissue.

10. A method for visualizing tissue comprising:

illuminating a tissue with at least one light-emitting diode light source selected from the group consisting of a fluorescent light source, a polarized white light source, and an unpolarized white light source; and

observing the tissue after illumination with the at least one light-emitting diode light source.

11. The method of claim 10 further comprising capturing an image of the illuminated tissue with a camera.

13. The method of claim 11 wherein the camera is a charge-coupled device camera.

14. The method of claim 10 further comprising measuring the intensity of light reflected from the tissue.