COATING FOR MEDICAL DEVICE AND METHOD OF MANUFACTURE

• US 20100215833A1
• Filed: 08/05/2009
• Published: 08/26/2010
• Est. Priority Date: 02/26/2009
• Status: Abandoned Application

• Current Assignee: Lothar Sellin
• Original Assignee: Lothar Sellin
• Inventors: Sellin, Lothar
• Application Number:
  US12/536,379
• Publication Number:
  US 20100215833A1
• Time in Patent Office: Days
• US Class Current: 427/2.250
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61L 27/28 Materials for coating prostheses
• CPC Class Codes: A61L 29/08 Materials for coatings
• CPC Class Codes: A61L 31/08 Materials for coatings
• CPC Class Codes: C08L 91/06 Waxes
• CPC Class Codes: C09D 193/00 Coating compositions based on natural resins; Coating compositions based on derivatives thereof based on polysaccharides C09D101/00 - C09D105/00; based on natural rubber C09D107/00; polishing compositions C09G
• CPC Class Codes: C09D 193/02 Shellac
• CPC Class Codes: C09D 5/1656 characterised by the film-forming substance C09D5/1637 takes precedence

Abstract

The invention relates to a medical device with a base body and a coating, wherein the coating exhibits film or lacquer-forming terpenoids. In addition, the coating of the medical device can exhibit at least one application-specific additive.

The invention further relates to a method for manufacturing such a device.

Claims

1. A coating for medical device comprising film or lacquer-forming terpenoids.

7. The coating according to claim 1, wherein the terpenoids are of natural, synthetic or semi-synthetic origin.

8. The coating according to claim 1, wherein the terpenoids belong to one of the following substance classes or contain mixtures thereof:

monoterpenes, sesquiterpenes, diterpenes, sesterterpenes, triterpenes and tetraterpenes.

9. The coating according to claim 1, comprising additional materials of organic or inorganic origin.

10. The coating according to claim 9, wherein the materials of inorganic origin are oxides and/or salts.

11. The coating according to claim 9, wherein the materials of inorganic origin are phosphates, sulfates, silicates, carbonates or mixtures thereof.

12. The coating according to one of claim 9, wherein the materials of organic origin are lipids or components thereof.

13. The coating according to claim 9, wherein the materials of organic origin are carbonic acids, its derivatives or substitution products.

14. The coating according to claim 1, wherein the coating exhibits shellol acid.

15. The coating according to claim 1, wherein the coating exhibits abietic acid.

16. The coating according to claim 1, wherein the coating exhibits shellac.

17. The coating according to claim 1, wherein the coating exhibits colophonium.

18. The coating according to claim 1, wherein the coating exhibits the resins dammar and/or mastic.

19. The coating according to claim 1, wherein the coating exhibits at least one application-specific additive.

20. The coating according to claim 19, wherein an additive is an anti-proliferatory, anti-inflammatory and/or anti-bacterial agent.

21. The coating according to claim 19, wherein an additive is a medication to reduce or prevent restenosis.

22. The coating according to one of claim 19, wherein an additive is an anti-mitotic agent.

23. The coating according to claim 22, wherein the anti-mitotic agent is paclitaxel.

24. The coating according to claim 19, wherein an additive is an immunosuppressor.

25. The coating according to claim 19, wherein an additive is an immunosuppressor from the group of linus derivatives, in particular rapamycin (sirolimus), everolimus, zoratolimus, biolimus, neolimus, and deforolimus.

26. The coating according to claim 19, wherein an additive is a growth factor inhibitor.

27. The coating according to claim 19, wherein the additive exhibits the shape of solid nano- or micro-particles or capsules.

31. The coating according to claim 1, wherein the device is one of a catheter, a vascular prostheses or a stent.

32. The coating according to claim 1, wherein a stent is mounted on the balloon catheter.

33. The coating according to claim 31, wherein the catheter is a balloon catheter.

2. (canceled)

3. (canceled)

4. (canceled)

5. (canceled)

6. (canceled)

28. A method for manufacturing a coating for a medical device comprising the steps of

adding solvents to terpenoid components

homogenizing the terpenoid components to form a homogeneous terpeniod solution;

and

applying the homogeneous terpenoid solution to the surface of a medical device.

29. The method according to claim 28, wherein the coating material is separated out onto the surface of the device via pressure reduction.

30. The method according to claim 28, wherein the solution is applied to the surface as the medical device rotates.