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PCR-FREE SAMPLE PREPARATION AND DETECTION SYSTEMS FOR HIGH SPEED BIOLOGIC ANALYSIS AND IDENTIFICATION

  • US 20100216657A1
  • Filed: 05/16/2007
  • Published: 08/26/2010
  • Est. Priority Date: 05/16/2006
  • Status: Abandoned Application
First Claim
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1. A sample preparation and analysis system suitable for conducting fluorescence based hybridization assays, the sample preparation and analysis system comprising:

  • a sample collection chamber capable of receiving a biological sample;

    a lysis chamber in fluidic communication with the sample collection chamber;

    a linear microfluidic array in fluidic communication with the lysis chamber, wherein the linear microfluidic array comprises a porous polymer monolith;

    optionally, a conduit in fluidic communication between the lysis chamber and the linear microfluidic array;

    a sample preparation module capable of being in fluidic communication with the lysis chamber, the linear microfluidic array, the optional conduit, or any combination thereof, the sample preparation module capable of controlling temperature of the lysis chamber, the linear microfluidic array, the optional conduit, or any combination thereof; and

    an optical excitation and detection system that is in optical communication with the linear microfluidic array.

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