WIREFRAME NANOSTRUCTURES
First Claim
1. A composition, comprising:
- a molecular structure defining a plurality of vertices and pathways, at least some of the vertices having at least three pathways emanating therefrom, each of which connects two vertices, wherein at least one pathway connecting two vertices comprises a nanotube comprising nucleic acid.
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Accused Products
Abstract
The present invention generally relates to nanotechnology and, in particular, to wireframe nanostructures which may be formed from nucleic acids. In various aspects, the invention relates to molecular structures having a plurality of vertices and pathways connecting the vertices, which may be formed from nucleic acids, including bundles or tubes of nucleic acids. Such molecular structures may form shapes such as icosahedrons, octahedrons, tetrahedrons, or other polyhedra, which may define an interior space. The interior space may be used, for example, to contain a molecule for further study, or to contain a molecule for drug delivery purposes. In some cases, the molecular structure may be stabilized using relatively short nucleic acid strands that interact with two or more nucleic acid portions within the structure, thereby substantially immobilizing the portions relative to each other. Other aspects of the invention relate to techniques for forming such molecular structures, techniques for using such molecular structures, techniques of promoting such molecular structures, kits involving such molecular structures, and the like.
25 Citations
78 Claims
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1. A composition, comprising:
a molecular structure defining a plurality of vertices and pathways, at least some of the vertices having at least three pathways emanating therefrom, each of which connects two vertices, wherein at least one pathway connecting two vertices comprises a nanotube comprising nucleic acid. - View Dependent Claims (2, 6, 7, 10, 12, 15, 16, 17, 22, 28, 30, 31, 32)
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3-5. -5. (canceled)
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8-9. -9. (canceled)
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11. (canceled)
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13-14. -14. (canceled)
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18-21. -21. (canceled)
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23-27. -27. (canceled)
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29. (canceled)
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33-42. -42. (canceled)
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43. A composition, comprising:
a molecular structure defining a plurality of vertices and pathways, at least some of the vertices having at least three pathways emanating therefrom, each of which connects two vertices, wherein at least one pathway connecting two vertices comprises a nucleic acid and has a length between the two vertices of at least about 40 nm. - View Dependent Claims (45, 47, 48, 49)
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44. (canceled)
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46. (canceled)
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50-76. -76. (canceled)
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77. A composition, comprising:
a molecular structure defining a three-dimensional interior space, the molecular structure being formed from one or more nucleic acids and having a smallest dimension of at least about 100 nm.
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78-118. -118. (canceled)
Specification