Device, system, and method for controllably reducing inflammatory mediators in a subject
2 Assignments
0 Petitions
Accused Products
Abstract
Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Extracorporeal devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject.
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Citations
113 Claims
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1-38. -38. (canceled)
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39. A method for treating an inflammatory disease or condition in a subject comprising:
providing an extracorporeal device including a treatment chamber configured to receive peripheral blood of the subject through a flow route, the treatment chamber including one or more reactive biological or chemical compounds that alter the functional structure of one or more inflammatory mediators in the peripheral blood. - View Dependent Claims (40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74)
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75-93. -93. (canceled)
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94. A system comprising:
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at least one computer program included on a computer-readable medium for use with at least one computer system wherein the computer program includes a plurality of instructions including, one or more instructions for determining at least one treatment of peripheral blood of a subject through an extracorporeal device including a treatment chamber configured to receive a peripheral blood through a flow route, the treatment chamber including one or more reactive biological or chemical compounds that alter a functional structure of one or more inflammatory mediators in the peripheral blood of the subject; one or more instructions for receiving data including data from a sensor configured to detect the one or more inflammatory mediators in the peripheral blood; and one or more instructions for receiving data including data from a controller for receiving the output of the sensor and configured to control interaction between the one or more biological or chemical compounds and the one or more inflammatory mediators in the treatment chamber;
wherein the sensor and the controller function relative to a target value of at least one of the one or more inflammatory mediators in the peripheral blood. - View Dependent Claims (95, 96, 97, 98, 99, 101, 102, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113)
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100. (canceled)
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103. (canceled)
Specification