Systems, Devices and Methods for Fluid/Drug Delivery

• US 20100217230A1
• Filed: 07/24/2007
• Published: 08/26/2010
• Est. Priority Date: 07/24/2006
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Medingo Ltd. (Roche Holding AG)
• Inventors: Iddan, Gavriel J., Yodfat, Ofer
• Granted Patent: US 8,435,211 B2
• Time in Patent Office: Days
• US Class Current: 604/506
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2209/04 Tools for specific apparatus
• CPC Class Codes: A61M 5/14232 Roller pumps
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type

Abstract

Fluid delivery systems, methods and devices for delivering a therapeutic fluid to the body of the patient are disclosed. A fluid delivery device for delivering fluid to the body of the patient includes a housing having an upper wall and a lower wall, wherein the upper wall includes an upper opening and the lower wall includes a lower opening, a well-arrangement mechanism configured to be disposed inside the housing and between the upper wall and the lower wall and including a tubular member having a bore, wherein the bore is configured to be disposed between the upper opening and the lower opening, and a penetrating cartridge for delivery of therapeutic fluid to the body of the patient, wherein the penetrating cartridge is configured to engage the bore following its insertion through the upper opening and the lower opening, wherein therapeutic fluid is configured to be delivered through the tubular member into the penetrating cartridge into the body of the patient when the penetrating cartridge engages the bore.

Claims

1. A fluid delivery device for delivering fluid to the body of the patient, comprising:

a housing having an upper wall and a lower wall defining an opening;

a well-arrangement mechanism configured to be disposed inside said housing and between said upper wall and said lower wall and including a tubular member having a bore, wherein said bore is configured to be disposed within said opening; and

a penetrating cartridge for delivery of therapeutic fluid to the body of the patient, wherein said penetrating cartridge is configured to engage said bore following its insertion through said opening;

wherein therapeutic fluid is configured to be delivered through said tubular member into said penetrating cartridge into the body of the patient when said penetrating cartridge engages said bore.

2. The fluid delivery device according to claim 1, further comprising:

a disposable part configured to include;

a reservoir containing therapeutic fluid; and

a delivery tube coupled to said reservoir, wherein said delivery tube is configured to be coupled to said tubular member of said well arrangement mechanism; and

a pump configured to pump therapeutic fluid from said reservoir into said delivery tube.

3. The fluid delivery device according to claim 2, wherein said disposable part further includes said well-arrangement mechanism.

4. The fluid delivery device according to claim 1, wherein said tubular member includes a lateral channel configured to provide delivery of therapeutic fluid to said bore of said tubular member.

5. The fluid delivery device according to claim 1, wherein said tubular member is configured to rotate about at least one axis.

6. The fluid delivery device according to claim 1, wherein said bore is configured to rotate about at least one axis.

7. The fluid delivery device according to claim 1, wherein the penetrating cartridge further comprises:

a body portion having;

a long lumen configured to extend longitudinally along said body portion;

at least one short lumen configured to extend transversely across said body portion and configured to be in fluid communication with said long lumen;

wherein said long lumen and said short lumen are further configured to be in fluid communication with said tubular member of said well-arrangement mechanism when said penetrating cartridge is inserted into said bore;

a cannula configured to be connected to said body portion;

a penetrating member configured to be inserted into said long lumen and said cannula, wherein said penetrating member is further configured to pierce the skin of the patient.

8. The fluid delivery device according to claim 7, wherein said penetrating member is configured to be removable from said cannula.

9. The fluid delivery device according to claim 7, wherein said long lumen and said short lumen are configured to be substantially perpendicular to each other.

10. The fluid delivery device according to claim 7, wherein said long lumen includes a sealing plug, said penetrating member is configured to pierce said sealing plug when said penetrating member is inserted into said long lumen;

and wherein said sealing plug is configured to seal said long lumen when said penetrating member is inserted into said long lumen.

11. The fluid delivery device according to claim 7, wherein said penetrating member includes a needle configured to pierce the skin of the patient.

12. The fluid delivery device according to claim 7, wherein said penetrating cartridge is configured to be inserted into said bore at an angle.

13. The fluid delivery device according to claim 12, wherein said cannula is configured to deliver therapeutic fluid to the body of the patient at said angle.

14. The fluid delivery device according to claim 7, wherein said opening is configured to accommodate rotational motion of said bore and said penetrating cartridge when said penetrating cartridge is inserted into said bore.

15. The fluid delivery device according to claim 1, wherein said penetrating cartridge is configured to be manually inserted into said bore.

16. The fluid delivery device according to claim 1, wherein said penetrating cartridge is configured to be automatically inserted into said bore.

17. The fluid delivery device according to claim 1, further comprising a tilting tool configured to rotate said bore prior to insertion of said penetrating cartridge into said bore.

18. The fluid delivery device according to claim 1, further comprising an inserter tool configured to secure said penetrating cartridge inside a housing of said inserter tool, wherein said inserter tool is configured to rotate said bore prior to insertion of said penetrating cartridge into said bore;

and upon said bore being rotated to a desired angle, said inserter tool is configured to insert said penetrating cartridge into said bore.

19. The fluid delivery device according to claim 18, wherein said inserter tool is configured to insert said penetrating cartridge into said bore manually.

20. The fluid delivery device according to claim 18, wherein said inserter tool is configured to insert said penetrating cartridge into said bore automatically.

21. The fluid delivery device according to claim 1, wherein the fluid delivery device is configured as a patch unit.

22. The fluid delivery device according to claim 1, wherein therapeutic fluid is delivered subcutaneously.

23. The fluid delivery device according to claim 1, wherein therapeutic fluid is insulin.

24. The fluid delivery device according to claim 1, wherein at least a portion of said disposable part is manufactured from plastic.

25. A method for delivery fluid to the body of the patient using a fluid delivery device having:

a housing having an upper wall and a lower wall defining an opening;

a well-arrangement mechanism configured to be disposed inside the housing and between the upper wall and the lower wall and including a tubular member having a bore, wherein the bore is configured to be disposed said opening; and

a penetrating cartridge for delivery of therapeutic fluid to the body of the patient, wherein the penetrating cartridge is configured to engage the bore following its insertion through said opening;

the method comprising the steps of;

inserting the penetrating cartridge into the bore of the well-arrangement mechanism until the penetrating cartridge engages the bore; and

delivering therapeutic fluid through the tubular member into the penetrating cartridge into the body of the patient.

26. The method according to claim 25, wherein said inserting step further comprises piercing the skin of the patient.

27. The method according to claim 25, further comprising:

rotating the bore of the well-arrangement mechanism prior to insertion of the penetrating cartridge to a desired angle;

inserting the penetrating cartridge into the bore until the penetrating cartridge engages the bore; and

delivering therapeutic fluid through the tubular member into the penetrating cartridge into the body of the patient.

28. A fluid delivery device for delivering therapeutic fluid to the body of a patient, comprising:

a patch unit including a disposable portion and a reusable portion;

said disposable portion including a well-arrangement provided between a first wall and a second wall;

a first aperture defined by at least one of said first wall and said second wall;

wherein said well-arrangement is configured to include

a tubular member having a bore,

an inlet port;

a delivery tube in fluid communication with said inlet port; and

a lateral channel between said inlet port and said bore.

29. The fluid delivery device according to claim 28, wherein said tubular member is configured to rotate such that said bore can be positioned in a plurality of positions relative to said first and/or second wall.

30. The fluid delivery device according to claim 29, further comprising a penetrating cartridge including a body portion, a cannula and a penetrating member configured to pierce the skin of the patient, wherein said body portion includes a first lumen for receiving fluid, and a second lumen in communication with said cannula and said first lumen.

31. A fluid delivery system for delivering a therapeutic fluid to the body of a patient comprising:

a fluid delivery device having a patch unit that including a disposable portion and a reusable portion, wherein said disposable portion includes;

a first wall having a first aperture;

a second wall having a second aperture;

a fluid delivery tube; and

a well-arrangement provided between said first wall and said second wall;

wherein said well-arrangement mechanism includes;

a tubular member having a bore;

an inlet port in fluid communication with said delivery tube, and

a lateral channel between said inlet port and said bore, wherein said tubular member is configured to rotate so that said bore can be configured to be positioned in a plurality of positions relative to said first and/or second wall of said disposable portion; and

a penetrating cartridge configured to be receivable in said bore of said tubular member;

wherein said penetrating cartridge includes;

a cannula;

a body portion; and

a penetrating member adapted to pierce said skin of a patient;

wherein said body portion includes;

 

a first lumen for receiving fluid; and

 

a second lumen in communication with said cannula and said first lumen.