DEVICES AND METHODS FOR PERCUTANEOUS ENERGY DELIVERY

• US 20100217253A1
• Filed: 02/25/2009
• Published: 08/26/2010
• Est. Priority Date: 06/15/2007
• Status: Abandoned Application

• Current Assignee: Primaeva Medical, Inc. (Syneron Incorporated)
• Original Assignee: Primaeva Medical, Inc. (Syneron Incorporated)
• Inventors: MEHTA, Bankim H.
• Application Number:
  US12/392,936
• Publication Number:
  US 20100217253A1
• Time in Patent Office: Days
• US Class Current: 606/33
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 18/203 applying laser energy to the outside of the body
• CPC Class Codes: A61B 2018/00005 Cooling or heating of the probe or tissue immediately surrounding the probe
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid
• CPC Class Codes: A61B 2018/0016 Energy applicators arranged in a two- or three dimensional array
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/00458 Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
• CPC Class Codes: A61B 2018/0047 Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
• CPC Class Codes: A61B 2018/00994 combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2018/143 multiple needles
• CPC Class Codes: A61B 2018/1467 using more than two electrodes on a single probe
• CPC Class Codes: A61B 2018/1475 Electrodes retractable in or deployable from a housing

Abstract

The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect.

Claims

1. An energy delivery system for delivering energy from to a target region beneath a surface of tissue, the device comprising:

a plurality of electrically isolated energy sources and a connector for coupling the energy supply unit;

a device body having a tissue engaging surface, where the tissue engaging surface allows orientation of the device body on the surface of tissue; and

a plurality of energy transfer units being advanceable from the device body at an oblique angle relative to the tissue engaging surface, where each energy transfer unit is coupleable via the connector to one electrically isolated energy source such that when energized, energy is prevented from passing between adjacent energy transfer units.

2. The energy delivery system of claim 1, where the plurality of electrically isolated energy sources are coupled to a power supply.

3. The energy delivery system of claim 1, where each energy transfer unit includes a pair of energy transfer elements each having an opposite polarity.

4. The energy delivery system of claim 1, where the electrically isolated energy source includes at least one isolation transformer to create a floating potential associated to the energy source, wherein the floating potential is connected to the energy transfer units.

5. The energy delivery system of claim 1, where at least one of the energy transfer units comprises a visual indicator for confirming depth of placement.

6. The energy delivery system of claim 1, further comprising a stabilization plate adjacent to the tissue engaging surface and being spaced from the plurality of energy transfer units

7. The energy delivery system of claim 6, wherein the tissue engaging surface and stabilization plate are positioned such that when the tissue engaging surface is placed on the surface of tissue and the plurality of energy transfer units is advanced into the surface of tissue at an entry point, the plurality of energy transfer units enters the tissue at the oblique angle relative to the tissue surface while the tissue engaging surface and the stabilization plate reduce movement of the surface of tissue adjacent to the entry point.

8. The energy delivery system of claim 7, further comprising a window located between the stabilization plate and the tissue engaging surface, where the window is configured to permit direct visualization of advancement of the energy transfer unit into the entry point.

9. The energy delivery system of claim 6, further comprising a cooling source coupled to the stabilization plate, such that the stabilization plate maintains a temperature at, below, or slightly above body temperature.

10. The energy delivery system of claim 9, where the cooling source comprises at least one heat pipe, where the heat pipe permits a portion of the cooling source to be located at a proximal end of the device body.

11. The energy delivery system of claim 9, where cooling source comprises a cooling source selected from the group consisting of a thermoelectric cooling device, a fluid cooling device, a phase-change type material that absorbs heat during the phase change.

12. The energy delivery system of claim 6, where the stabilization plate further comprises a suction lumen.

13. The energy delivery system of claim 6, further comprising a display unit located on a portion of the device body.

14. The energy delivery system of claim 13, where the display unit is configured to display one or more parameters of at least one of the energy sources.

15. The energy delivery system of claim 13, where the display unit is configured to display one or more parameters of at least one of the energy sources,

16. The energy delivery system of claim 1, where each of the energy transfer units has a respective impedance along a respective active region, and wherein the impedance of at least one of the energy transfer units varies along its respective active region.

17. The energy delivery system of claim 16, where the impedance of each of the energy transfer units varies along the respective active region.

18. The energy delivery system of claim 1, where at least one of the energy transfer unit comprises a sensor for measuring at least one tissue parameter.

19. The energy delivery system of claim 18, where the sensor is a temperature sensor located within the at least one of the energy transfer elements.

20. The energy delivery system of claim 18, where the least one tissue parameter comprises electrical impedance, the phase angle of the electrical impedance, acoustic impedance, hydration, moisture content, electromagnetic reflectance/absorption, temperature, movement, and elasticity.

21. The energy delivery system of claim 1, where the energy supply unit comprises an RF energy supply unit and where the electrically isolated energy sources comprise electrically isolated RF energy sources.

22. The energy delivery system of claim 21, further comprising a temperature sensor coupled to at least one energy transfer unit.

23. The energy delivery system of claim 22, further comprising at least one controller coupled to the temperature sensor, where the controller is configured to control an output level of the associated isolated RF energy source.

24. The energy delivery system of claim 23, where each isolated RF energy source is independently controlled by an associated controller.

25. A system for applying energy to a target layer of tissue within a plurality of tissue layers to improve a cosmetic appearance of the tissue, the system comprising:

a plurality of energy transfer units coupled to a device body, each energy transfer unit having at least one probe having an active area, where at least one of the probes is configured to measure a tissue parameter within the active area; and

a power supply comprising a plurality of electrically isolated energy sources, each electrically isolated energy source being coupled to one energy transfer unit to form a plurality of treatment circuits such that energy from the power supply is limited from passing between different treatment circuits to produce a plurality of fractional lesions in the tissue layer where each fractional lesion is separated from an adjacent fractional lesion by a region of viable tissue.

26. The system of claim 25, wherein the tissue parameter is a temperature of the tissue.

27. The system of claim 25, where the power supply includes at least one controller to adjust energy delivery to the probes in response to the tissue parameter.

28. The system of claim 27, where the controller is configured to adjust energy delivery to the probes in response to the tissue impedance.

29. The system of claim 25, where each probe includes an active area and each probe is configured measure the tissue parameter adjacent to the respective active area.

30. The system of claim 25, where at least one of the probes comprises a first sensor located on the active area.

31. The system of claim 25, where at least one of the probes comprises a second sensor located on a non-active area of the probe.

32. The system of claim 25, where the parameter comprises an impedance value of the tissue.

33. The system of claim 32, wherein the controller adjusts energy delivery based on the impedance value of tissue.

34. The system of claim 33, where the controller prevents energy delivery to at least one of the probes when the tissue parameter is less than 250 ohms or greater than 3000 ohms.

35. The system of claim 33, where the controller provides energy delivery to at least one of the probes using a first set of parameters when the tissue parameter is between 700 and 1500 ohms.

36. The system of claim 33, where the controller provides energy delivery to at least one of the probes using a second set of parameters when the tissue parameter is between 1500 and 3000 ohms.

37. The system of claim 33, where the controller provides energy delivery to at least one of the probes using a second set of parameters between 250 and 700 ohms.

38. The system of claim 32, where the plurality of probes comprises a plurality of pairs of probes where each fractional lesion is created between adjacent pairs of probes.

39-83. -83. (canceled)