Analyte Sensor Offset Normalization
First Claim
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1. A method of calculating the amount of an analyte in a fluid using a biosensor comprising:
- providing said biosensor comprising a blank electrode and a working electrode;
receiving measurements of current from said working electrode and current from said blank electrode;
determining a normalization ratio corresponding to a ratio of the surface areas of said working electrode and said blank electrode; and
correcting an offset between the two electrodes using said normalization ratio.
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Abstract
Measurements of current from a working electrode and current from a blank electrode are received and a ratio corresponding to the ratio of surface areas of the working electrode and the blank electrode is determined. This ratio is used to correct any differential current offset between an analyte (working) electrode and a control (blank) electrode to yield a more accurate net current output. Systems, methods and computer program products are further described for measuring an analyte concentration disclosed are for calculating the amount of an analyte in a fluid using a biosensor.
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Citations
24 Claims
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1. A method of calculating the amount of an analyte in a fluid using a biosensor comprising:
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providing said biosensor comprising a blank electrode and a working electrode; receiving measurements of current from said working electrode and current from said blank electrode; determining a normalization ratio corresponding to a ratio of the surface areas of said working electrode and said blank electrode; and correcting an offset between the two electrodes using said normalization ratio. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method of calculating the amount of an analyte in a fluid using a biosensor, the method comprising:
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providing said biosensor comprising a working electrode and a blank electrode; determining a ratio of measured current from said working electrode and current measured from said blank electrode; and calculating in said biosensor a net working current by subtracting said blank electrode current from a corrected working electrode current, said corrected working electrode current is determined by multiplying said measured working electrode current by said ratio. - View Dependent Claims (16, 17)
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18. A system for calculating the amount of an analyte in a fluid using a biosensor comprising:
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a biosensor capable of sensing an analyte in the fluid and outputting a signal corresponding to an analyte concentration in the fluid, said biosensor comprising a working electrode and a blank electrode; a controller configured to measure current from each of said electrodes; and a processing unit in communication with said biosensor, wherein said processing unit is configured to respond to computer instructions to; determine a normalization ratio corresponding to a ratio of the surface areas of said working electrode and said blank electrode; and correct a differential current offset using said normalization ratio. - View Dependent Claims (19, 20, 21, 22)
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23. A computer program product for calculating the amount of an analyte in a fluid using a biosensor, said computer program product comprising:
a computer usable medium having computer usable program code embodied therein, the computer usable medium comprising; computer usable program code configured for receiving measurements of current from a working electrode and current from a blank electrode; computer usable program code configured for determining a ratio of said working electrode and said blank electrode; and computer usable program code configured for correcting an offset of said net working current by multiplying said ratio times said blank electrode current resulting in a corrected blank electrode current. - View Dependent Claims (24)
Specification