METHODS AND DEVICES FOR DELIVERING INJECTIONS

• US 20100222810A1
• Filed: 10/02/2009
• Published: 09/02/2010
• Est. Priority Date: 01/18/2002
• Status: Abandoned Application

• Current Assignee: Martin Dieck, Nicholas Debeer
• Original Assignee: Martin Dieck, Nicholas Debeer
• Inventors: DeBEER, Nicholas, DIECK, Martin
• Application Number:
  US12/573,065
• Publication Number:
  US 20100222810A1
• Time in Patent Office: Days
• US Class Current: 606/213
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61B 2017/00597 Implements comprising a membrane
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/00623 Introducing or retrieving devices therefor
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/00986 Malecots, e.g. slotted tubes, of which the distal end is pulled to deflect side struts
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

Septal defect occluders are disclosed which can be used with a catheter deployment system to occlude a septal defect. The septal defect occluders of the present invention comprise a metallic frame structure that supports a biodegradable member. The frame structure is made from a shape memory metal such as Nitinol. The frame forms two opposing umbrella or disc shaped halves that are connected via a central region. The biodegradable member is attached to the umbrella or disc shaped halves and can be any of numerous biodegradable materials and is preferably a co-polymer of glycolide and lactide. This material initially forms a barrier to blood flow that occludes the defect. Over time, this material is replaced by the body with scar tissue formation and endothelial cells. The metal frame is left coated with the body'"'"'s own material that blocks the defect.

Claims

1-20. -20. (canceled)

21. A septal defect occluder comprising:

a support member having a first inflatable ring, a second inflatable ring and a membrane joined to said first and second rings at a common center thereof; and

an adhesive material adapted to fill said first and second rings upon deployment of said support member in a septal defect.

22. The septal defect occluder of claim 21, wherein said support member is comprised of a biodegradable/biocompatible member.

24. The septal defect occluder of claim 21, wherein the adhesive material is a curable adhesive material.

25. The septal defect occluder of claim 21, further comprising at least one valve located in the support member, where the valve configures the support member to be inflatable with the adhesive material.

26. The septal defect occluder of claim 25, where the valve is located in at least the first or second inflatable ring.

27. The septal defect occluder of claim 21, where the first, second, and common membranes are bio-absorbable.

28. The septal defect occluder of claim 21, where the first inflatable ring and second inflatable ring comprise solid disc shapes.

30. The occluder device of claim 24, wherein the adhesive material is a curable adhesive material.

31. The occluder device of claim 24, further comprising at least one valve located in the support member, where the valve configures the support member to be inflatable with the adhesive material.

32. The occluder device of claim 26, where the valve is located in at least the first or second ring member.

33. The occluder device of claim 24, where the first, second, and common membranes are bio-absorbable.

34. The occluder device of claim 24, where the first ring member and second ring member comprise solid disc shapes.

23. A method of occluding a septal defect comprising the steps of:

(a) accessing the right side of the heart via a catheter;

(b) advancing the catheter through the septal defect;

(c) advancing a septal defect occluder having proximal and distal ends with a shape memory frame and a biodegradable/biocompatible member through the catheter;

(d) allowing the distal end of the occluder to form a preset shape in the left side of the heart;

(e) withdrawing the catheter and the occluder slowly until the distal end contacts the heart tissue around the opening of the defect;

(f) withdrawing the catheter until the occluder is fully deployed in the heart and the proximal end has formed its preset shape; and

(g) removing the catheter from the patient;

(h) allowing the body to degrade the biodegradable member and cover the frame with native tissue.

29. An occluder device for placing within a septal defect, the occluder device comprising:

a support member comprising a first ring member having a first membrane and second ring member having a second membrane, where the first and second ring members join together to form a center section having a common membrane; and

an adhesive material located in the first and second ring members, where on deployment the first and second ring members can be placed on either side of a septum such that the center membrane resides within the septal defect.

35. A method of occluding a septal defect comprising the steps of:

accessing the right side of the heart via a catheter;

advancing the catheter to the septal defect;

advancing a septal defect occluder having a support member comprising a two ring members connected by a center member;

inflating the support member with a curable adhesive to allow the ring members to form a preset shape on either side of a septum; and

withdrawing the catheter and removing the catheter from the patient.

36. The method of claim 35, where inflating the support member comprises inflating the support member through a valve in the support member.

37. The method of claim 35, where the support member comprises a bioabsorbable membrane such that after withdrawing the catheter the absorbable membrane degrades is subsequently absorbed within the body.