HEMODIALYSIS AND PERITONEAL DIALYSIS SYSTEMS HAVING ELECTRODEIONIZATION CAPABILITIES

• US 20100224492A1
• Filed: 03/05/2010
• Published: 09/09/2010
• Est. Priority Date: 03/06/2009
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc., EMD Millipore Corporation (Merck & Co., Inc.)
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Miller, Joshua James, Ding, Yuanpang Samuel, Rohde, Justin, Karoor, Sujatha, Lo, Ying-Cheng
• Granted Patent: US 8,858,792 B2
• Time in Patent Office: Days
• US Class Current: 204/535
• CPC Class Codes: A61M 1/1674 using UV radiation sources for sterilising the dialysate
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2202/0014 removed from the body
• CPC Class Codes: B01D 61/243 Dialysis
• CPC Class Codes: B01D 61/44 Ion-selective electrodialysis
• CPC Class Codes: B01D 61/58 Multistep processes

Abstract

Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source and an electrodeionization unit. The carbon source and urease source can be in the form of removable cartridges.

Claims

1. A dialysis fluid recycling system comprising:

a carbon source;

a urease source in fluid communication with the carbon source; and

an electrodeionization unit in fluid communication with the urease source.

2. The dialysis fluid recycling system of claim 1, which includes an ion exchange unit in fluid communication with the electrodeionization unit.

3. The dialysis fluid recycling system of claim 1, which includes a metering source in fluid communication with the electrodeionization unit.

4. A hemodialysis system comprising:

a carbon source;

a urease source in fluid communication with the carbon source;

an electrodeionization unit in fluid communication with the urease source; and

a dialyzer in fluid communication with the electrodeionization unit.

5. The hemodialysis system of claim 4, which includes an ion exchange unit in fluid communication with the dialyzer.

6. The hemodialysis system of claim 4, which includes a metering source in fluid communication with the dialyzer.

7. The hemodialysis system of claim 4, which includes a filter in fluid communication with the dialyzer.

8. The hemodialysis system of claim 4, which includes an ultraviolet bactericidal light in fluid communication with the dialyzer.

9. A peritoneal dialysis system comprising:

a carbon source;

a urease source in fluid communication with the carbon source; and

an electrodeionization unit in fluid communication with the urease source.

10. The peritoneal dialysis system of claim 9, which includes an ion exchange unit in fluid communication with the electrodeionization unit.

11. The peritoneal dialysis system of claim 9, which includes a metering source in fluid communication with the electrodeionization unit.

12. The peritoneal dialysis system of claim 9, which includes a filter in fluid communication with the electrodeionization unit.

13. The peritoneal dialysis system of claim 9, which includes an ultraviolet bactericidal light in fluid communication with the electrodeionization unit.

14. A method of performing hemodialysis comprising:

passing a spent dialysis fluid from a dialyzer through a carbon source, a urease source and an electrodeionization unit to produce a clean dialysis fluid; and

passing the clean dialysis fluid through the dialyzer.

15. The method of claim 14, which includes passing the clean dialysis fluid through an ion exchange unit before the clean dialysis fluid passes through the dialyzer.

16. The method of claim 14, which includes adding at least one dialysis component to the clean dialysis fluid before the clean dialysis fluid passes through the dialyzer.

17. A method of performing peritoneal dialysis comprising:

passing a spent dialysis fluid from an individual through a carbon source, a urease source and an electrodeionization unit to produce a clean dialysis fluid; and

returning the clean dialysis fluid to the individual.

18. The method of claim 17, which includes passing the clean dialysis fluid through an ion exchange unit before the clean dialysis fluid returns to the patient.

19. The method of claim 17, which includes adding at least one dialysis component to the clean dialysis fluid before the clean dialysis fluid returns to the individual.

20. The method of claim 17, which includes passing the clean dialysis fluid through a filter before the clean dialysis fluid returns to the patient.

21. The method of claim 17, which includes passing the clean dialysis fluid through an ultraviolet bactericidal light before the clean dialysis fluid returns to the patient.

22. A method of performing dialysis comprising:

passing a spent dialysis fluid through a dialysis compartment of a dialyzer comprising an ion-rejection membrane that allows the passage of negatively charged ions and nonionic species but restricts the passage of positively charged ions, the ion-rejection membrane separating the dialysis compartment from a dialysate compartment of the dialyzer;

passing used dialysis fluid generated from the dialysate compartment of the dialyzer through a carbon source, a urease source and an electrodeionization unit to produce a clean dialysis fluid;

adding a source of negative ions to the clean dialysis fluid; and

and passing the clean dialysis fluid through the dialysate compartment of the dialyzer.

23. A method of performing dialysis comprising:

passing a spent dialysis fluid through a dialysis compartment of a dialyzer comprising an ion-rejection membrane that allows the passage of positively charged ions and nonionic species but restricts the passage of negatively charged ions, the ion-rejection membrane separating the dialysis compartment from a dialysate compartment of the dialyzer;

passing used dialysis fluid generated from the dialysate compartment of the dialyzer through a carbon source, a urease source and an electrodeionization unit to produce a clean dialysis fluid;

adding a source of positive ions to the clean dialysis fluid; and

and passing the clean dialysis fluid through the dialysate compartment of the dialyzer.