Therapeutic and Directionally Dosed Implants

• US 20100228074A1
• Filed: 08/24/2007
• Published: 09/09/2010
• Est. Priority Date: 08/25/2006
• Status: Abandoned Application

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Drobnik, Michael W., Drobnik, Christopher D.
• Application Number:
  US12/377,480
• Publication Number:
  US 20100228074A1
• Time in Patent Office: Days
• US Class Current: 600/7
• CPC Class Codes: A61B 2050/0058 closable by translation
• CPC Class Codes: A61K 9/7007 Drug-containing films, membranes or sheets A61K9/0041, A61K9/0043, A61K9/006, A61K9/0063 take precedence
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque
• CPC Class Codes: A61N 2005/101 Magazines or cartridges for seeds
• CPC Class Codes: A61N 2005/1023 Means for creating a row of seeds, e.g. spacers
• CPC Class Codes: A61N 2005/1024 Seeds
• CPC Class Codes: A61N 5/1001 using radiation sources introduced into or applied onto the body; brachytherapy
• CPC Class Codes: A61N 5/1027 Interstitial radiation therapy

Abstract

The present disclosure relates to an implant comprising at least one sheet of a biocompatible material, at least one shielding apparatus fixed to the biological material, and at least one radioactive seed partially disposed in the shielding apparatus. The disclosure also relates to a method for treating a patient, comprising fixing to the tissue of the patient at least one implant comprising at least one sheet of a biocompatible material, at least one shielding apparatus fixed to the biological material, and at least one radioactive seed partially disposed in the shielding apparatus.

Claims

1. An implant comprising:

at least one sheet of a biocompatible material;

at least one shielding apparatus fixed to the biocompatible material; and

at least one radioactive seed partially disposed in the shielding apparatus.

2. The implant according to claim 1, comprising a plurality of radioactive seeds.

3. The implant according to claim 1, wherein the radioactive seed is at least substantially fixed into a position by the shielding material.

4. The implant according to claim 1, wherein two sheets of a biocompatible material are bonded together at a perimeter around said at least one radioactive seed, and the at least one radioactive seed is partially disposed in the shielding apparatus.

5. The implant according to claim 1, wherein the shielding apparatus is comprises gold.

6. The implant according to claim 1, wherein at least a portion of the biocompatible material is a bioabsorbable material.

7. The implant according to claim 1, wherein at least one of the biocompatible material and the shielding apparatus comprise at least one of a fiducial marker, a visual marker, a coating, and an attachment feature.

8. The implant according to claim 1, wherein the at least one sheet of a biocompatible material comprises a radiation-shielding material.

9. The implant according to claim 8, wherein the radiation-shielding material is a polymeric material containing at least one of bismuth and barium.

10. The implant according to claim 1, wherein the at least one sheets of biocompatible material is an open-knit mesh.

11. The implant according to claim 10, wherein the open-knit mesh is coated with at least one biological material.

12. The implant according to claim 1, wherein the seeds are disposed in a planar array.

13. The implant according to claim 1, wherein the seeds are disposed in a three-dimensional array in the at least one sheet of biocompatible materials.

14. A method for treating a patient, comprising fixing to the tissue of the patient at least one implant according to claim 1.

15. The method according to claim 14, further comprising treating the patient with at least one additional therapy.

16. The method according to claim 15, wherein the at least one additional therapy is chosen from chemotherapy and external beam radiation.

17. The method according to claim 14, wherein said implant is fixed to the tissue by at least one of sutures, staples, tacks, adhesives, and chevrons.

18. The method according to claim 14, wherein the implant is laproscopically inserted into the patient.