SYSTEMS AND METHODS FOR MONITORING DP, IVRT, DiFT, DIASTOLIC FUNCTION AND/OR HF
First Claim
1. For use with an implantable system, a method comprising:
- (a) using an implanted sensor to obtain a signal indicative of changes in a patient'"'"'s arterial blood volume for a period of time corresponding to one or more cardiac cycles;
(b) using implanted electrodes to obtain a signal indicative of electrical activity of the patient'"'"'s heart for the period of time;
(c) detecting a beginning of a diastolic period (DP) based on a feature of the signal indicative of changes in arterial blood volume;
(d) detecting an end of the DP based on a feature of the signal indicative of electrical activity of the patient'"'"'s heart; and
(e) estimating the DP, an isovolumic relaxation time (IVRT) and/or a diastolic filling time (DiFT) based on the beginning of the DP as detected at step (c) and the end of the DP as detected at step (d).
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Accused Products
Abstract
Implantable systems, and methods for use therewith, are provided for monitoring a patient'"'"'s diastolic function and/or heart failure (HF) condition. A signal indicative of changes in arterial blood volume and a signal indicative of electrical activity of the patient'"'"'s heart are obtained. Beginnings of diastolic periods can be detected based on a feature of the signal indicative of changes in arterial blood volume. Ends of the diastolic periods can be detected based on a feature of the signal indicative of electrical activity of the patient'"'"'s heart, or on the signal indicative of changes in arterial blood volume. Diastolic periods (DPs), isovolumic relaxation times (IVRTs) and/or diastolic filling times (DiFTs) can be estimated based on the detected beginnings of the diastolic periods and detected ends of the diastolic periods. The patient'"'"'s diastolic function and/or HF condition (and/or changes therein) can be monitored based on the estimates of DP, IVRT and/or DiFT.
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Citations
27 Claims
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1. For use with an implantable system, a method comprising:
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(a) using an implanted sensor to obtain a signal indicative of changes in a patient'"'"'s arterial blood volume for a period of time corresponding to one or more cardiac cycles; (b) using implanted electrodes to obtain a signal indicative of electrical activity of the patient'"'"'s heart for the period of time; (c) detecting a beginning of a diastolic period (DP) based on a feature of the signal indicative of changes in arterial blood volume; (d) detecting an end of the DP based on a feature of the signal indicative of electrical activity of the patient'"'"'s heart; and (e) estimating the DP, an isovolumic relaxation time (IVRT) and/or a diastolic filling time (DiFT) based on the beginning of the DP as detected at step (c) and the end of the DP as detected at step (d). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. For use with an implantable system, a method for monitoring a patient'"'"'s diastolic function and/or heart failure (HF) condition, comprising:
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obtaining a signal indicative of changes in arterial blood volume and a signal indicative of electrical activity of the patient'"'"'s heart; detecting beginnings of diastolic periods based on a feature of the signal indicative of changes in arterial blood volume, and ends of the diastolic periods based on a feature of the signal indicative of electrical activity of the patient'"'"'s heart; and estimating the patient'"'"'s diastolic periods (DPs), isovolumic relaxation times (IVRTs) and/or diastolic filling times (DiFTs) based on the detected beginnings of the diastolic periods and detected ends of the diastolic periods; and monitoring the patient'"'"'s diastolic function and/or HF, and/or changes in the patient'"'"'s diastolic function and/or HF, based on estimates of DP, IVRT and/or DiFT. - View Dependent Claims (20)
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21. An implantable system, comprising:
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an implantable sensor to obtain a signal indicative of changes in arterial blood volume; a sensing circuit to obtain a signal indicative of electrical activity of the patient'"'"'s heart; a monitor configured to detect beginnings of diastolic periods based on a feature of the signal indicative of changes in arterial blood volume, detect ends of the diastolic periods based on a feature of the signal indicative of electrical activity of the patient'"'"'s heart, and estimate diastolic periods (DPs), isovolumic relaxation times (IVRTs) and/or diastolic filling times (DiFTs) based on the detected beginnings of the diastolic periods and the detected ends of the diastolic periods. - View Dependent Claims (22, 23)
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24. For use with an implantable system, a method comprising:
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(a) using an implanted sensor to obtain a signal indicative of changes in a patient'"'"'s arterial blood volume for a period of time corresponding to one or more cardiac cycles; (b) detecting a beginning of a diastolic period (DP) based on a first feature of the signal indicative of changes in arterial blood volume; (c) detecting an end of the DP based on a second feature of the signal indicative of changes in arterial blood volume; and (d) estimating the DP, an isovolumic relaxation time (IVRT) and/or a diastolic filling time (DiFT) based on the beginning of the DP as detected at step (b) and the end of the DP as detected at step (c). - View Dependent Claims (25)
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26. An implantable system, comprising:
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an implantable sensor to obtain a plethysmography signal indicative of changes in arterial blood volume; a monitor configured to detect beginnings and ends of diastolic periods based on features of the plethysmography signal indicative of changes in arterial blood volume, and estimate diastolic periods (DPs), isovolumic relaxation times (IVRTs) and/or diastolic filling times (DiFTs) based on the detected beginnings of the diastolic periods and the detected ends of the diastolic periods. - View Dependent Claims (27)
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Specification