MEDICAL DEVICE FOR MODIFICATION OF LEFT ATRIAL APPENDAGE AND RELATED SYSTEMS AND METHODS

• US 20100228279A1
• Filed: 01/08/2010
• Published: 09/09/2010
• Est. Priority Date: 01/08/2009
• Status: Active Grant

• Current Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Original Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Inventors: Edmiston, Daryl R., Miles, Scott D., Davis, Clark C.
• Granted Patent: US 8,795,328 B2
• Time in Patent Office: Days
• US Class Current: 606/198
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 17/0487 Suture clamps, clips or locks, e.g. for replacing suture knots; Instruments for applying or removing suture clamps, clips or locks suture anchors A61B17/0401; wound clamps or clips A61B17/08; ligaturing clamps or clips A61B17/122
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/1204 temporary occlusion
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12131 characterised by the type of occluding device
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/122 Clamps or clips , e.g. for the umbilical cord for the vas deferens A61F6/206
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00579 Barbed implements
• CPC Class Codes: A61B 2017/00588 Rigid or stiff implements, e.g. made of several rigid parts linked by hinges
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00597 : Implements comprising a membrane
• CPC Class Codes: A61B 2017/00601 : Implements entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2017/0061 : Implements located only on one side of the opening
• CPC Class Codes: A61B 2017/00632 : Occluding a cavity, i.e. closing a blind opening
• CPC Class Codes: A61B 2017/00867 : shape memory effect
• CPC Class Codes: A61B 2017/00884 : enhancing wound closure
• CPC Class Codes: A61B 2017/0409 : Instruments for applying suture anchors
• CPC Class Codes: A61B 2017/0412 : having anchoring barbs or pins extending outwardly from suture anchor body
• CPC Class Codes: A61B 2017/0414 : having a suture-receiving opening, e.g. lateral opening
• CPC Class Codes: A61B 2017/0437 : the barbs being resilient or spring-like
• CPC Class Codes: A61B 2017/0446 : Means for attaching and blocking the suture in the suture anchor
• CPC Class Codes: A61B 2017/0448 : Additional elements on or within the anchor
• CPC Class Codes: A61B 2017/0459 : Multiple holes in the anchor through which the suture extends and locking the suture when tension is applied
• CPC Class Codes: A61B 2017/0464 : for soft tissue
• CPC Class Codes: A61B 2017/1205 : Introduction devices
• CPC Class Codes: Y10T 29/49826 : Assembling or joining

Abstract

A medical device and system for modifying a left atrial appendage (“LAA”), as well as related methods, are provided. In accordance with one embodiment, a medical device includes a plurality of discrete frame segments coupled with at least one ring member to form a frame structure. Each discrete frame segment includes an expanding leg, a collapsing leg and a hub extension. A tissue growth member is coupled with the plurality of discrete frame segments to define a substantially convex surface and a substantially concave surface.

Claims

1. A medical device for modifying an atrial appendage, the medical device comprising:

a plurality of discrete frame segments coupled with at least one ring member to form a frame structure, each discrete frame segment comprising;

an expanding leg;

a collapsing leg; and

a hub extension;

a tissue growth member coupled with the plurality of discrete frame segments to define a substantially convex surface and a substantially concave surface.

2. The medical device of claim 1, wherein the tissue growth member comprises a porous foam material.

3. The medical device of claim 2, wherein the tissues growth member further comprises expanded polytetrafluoroethylene.

4. The medical device of claim 1, wherein the plurality of discrete frame segments are formed of a nickel-titanium alloy.

5. The medical device of claim 1, wherein each expanding leg is coplanar with its associated collapsing leg and its associated hub extension.

6. The medical device of claim 1, wherein the plurality of discrete frame segments are cooperatively configured to define a central opening therethrough.

7. The medical device of claim 1, wherein at least a portion of each collapsing leg is positioned adjacent the convex surface of the tissue growth member.

8. The medical device of claim 7, wherein at least a portion of each expanding leg is positioned adjacent the concave surface of the tissue growth member.

9. The medical device of claim 1, wherein each discrete frame segment includes at least one clip member configured to attach to the tissue growth member.

10. The medical device of claim 9, wherein the at least one clip member is associated with the collapsing leg.

11. The medical device of claim 9, wherein the at least one clip member is associated with the expanding leg.

12. The medical device of claim 9, wherein the at least one clip member further includes a base portion, a cantilevered extension having a free end, and a pawl configured to engage the free end of the cantilevered extension.

13. The medical device of claim 12, wherein the at least one clip member further includes one or more nubs associated with the base portion.

14. The medical device of claim 13, wherein the at least one clip member is integrally formed with its associated discrete frame segment.

15. The medical device system comprising:

a medical device comprising;

a plurality of discrete frame segments coupled with at least one ring member to form a frame structure, each discrete frame segment comprising;

an expanding leg;

a collapsing leg; and

a hub extension;

a tissue growth member coupled with the plurality of discrete frame segments to define a substantially convex surface and a substantially concave surface;

a catheter; and

a pusher member configured to displace the medical device relative to the catheter.

16. The medical device system of claim 15, wherein the pusher member is releaseably coupled with the medical device.

17. The medical device system of claim 16, wherein the pusher member is threadably coupled with the medical device.

18. The medical device system of claim 16, wherein the hub extensions are in a first state when the pusher member is coupled with the medical device, and wherein the hub extensions are in a second state with the pusher member is released from the medical device.

19. The medical device of claim 15, wherein the tissue growth member comprises a porous foam material.

20. The medical device of claim 19, wherein the tissues growth member further comprises expanded polytetrafluoroethylene.

21. A method of forming a medical device, the method comprising:

forming a plurality of discrete frame segments, each discrete frame segment including an expanding leg, a collapsing leg, and a hub extension;

coupling the hub extension of each of the plurality of discrete frame segments with at least one ring member; and

coupling a tissue growth member with the plurality of discrete frame segments.

22. The method according to claim 21, wherein coupling a tissue growth member with the plurality of discrete frame segments further includes forming a substantially concave surface and a substantially convex surface.

23. The method according to claim 22, further comprising positioning the expanding legs adjacent the substantially concave surface and positioning the collapsing legs adjacent the substantially convex surface.

24. The method according to claim 21, further comprising forming the tissue growth member to include a first layer of a porous foam material and a second layer of expanded polytetrafluoroethylene.

25. The method according to claim 21, further comprising forming the expanding leg, collapsing leg and hub extension of a given discrete frame segment to be substantially coplanar.

26. The method according to claim 21, wherein forming a plurality of discrete frame segments includes cutting each discrete frame member from a substantially flat sheet of nickel-titanium alloy.