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DRUG COATED EXPANDABLE DEVICES

  • US 20100233236A1
  • Filed: 05/21/2010
  • Published: 09/16/2010
  • Est. Priority Date: 03/31/2008
  • Status: Active Grant
First Claim
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1. A medical device comprising:

  • an expandable member having a first diameter for insertion into a vessel and a second diameter for making contact with the vessel walls; and

    a liquid formulation of a rapamycin affixed to at least a portion of the surface of the expandable member, the liquid formulation of a rapamycin comprising about 50 mg/ml of a rapamycin, about 5 mg/ml of a first excipient selected from the group of polymers consisting of PEG 400, PEG 1000, PEG 1500, PEG 2000 and polyvinyl alcohol, about 5 mg/ml of a second excipient selected from the group of antioxidants consisting of BHT, BHA and vitamin E TPGS, ascorbyl palmitate, resveratrol, and acetone and water in a ratio of about 60/40 to about 75/25.

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