Analyte Sensor Calibration Management

• US 20100234710A1
• Filed: 04/16/2010
• Published: 09/16/2010
• Est. Priority Date: 03/28/2008
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Doniger, Kenneth J., Budiman, Erwin Satrya, Harper, Wesley Scott, Dunn, Timothy Christian
• Granted Patent: US 8,583,205 B2
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes

Abstract

Methods, devices, and systems for calibrating an analyte sensor are provided. Embodiments include determining a sensitivity value associated with an analyte sensor, retrieving a prior sensitivity value associated with the analyte sensor, determining whether a variance between the determined sensitivity value and the retrieved prior sensitivity value is within a predetermined sensitivity range, determining a composite sensitivity value based on the determined sensitivity value and the retrieved prior sensitivity value, and assigning a successful calibration sensitivity value based on the retrieved prior sensitivity value when the variance is within the predetermined sensitivity range.

Claims

1. A method for calibrating an analyte sensor, comprising:

determining a sensitivity value associated with an analyte sensor;

retrieving a prior sensitivity value associated with the analyte sensor;

determining whether a variance between the determined sensitivity value and the retrieved prior sensitivity value is within a predetermined sensitivity range;

determining a composite sensitivity value based on the determined sensitivity value and the retrieved prior sensitivity value; and

assigning a successful calibration sensitivity value based on the retrieved prior sensitivity value when the variance is within the predetermined sensitivity range.

2. The method as recited in claim 1, further comprising:

determining a second sensitivity value associated with the analyte sensor after determining a composite sensitivity value;

determining whether a second variance between the second determined sensitivity value and the composite sensitivity value is within a predetermined sensitivity range; and

determining a second composite sensitivity value based on the second determined sensitivity value and the successful calibration sensitivity value when the second variance is within the predetermined sensitivity range.

3. The method as recited in claim 1, further comprising:

requesting a blood glucose value when the variance is outside the predetermined sensitivity range and a successful calibration sensitivity value has not been assigned.

4. The method of claim 3 wherein requesting a blood glucose value includes prompting a user to input a blood glucose information.

5. The method of claim 1 wherein the two sensitivity values are determined sequentially.

6. The method of claim 1 wherein the determined composite sensitivity includes a weighted average of the determined sensitivity value and the retrieved sensitivity value.

7. The method of claim 1, wherein the analyte sensor is a glucose sensor.

8. An apparatus, comprising:

a processing unit; and

a memory operatively coupled to the processing unit, the memory storing instructions which, when executed by the processing unit, causes the processing unit to;

determine a sensitivity value associated with an analyte sensor;

retrieve a prior sensitivity value associated with the analyte sensor;

determine whether a variance between the determined sensitivity value and the retrieved prior sensitivity value is within a predetermined sensitivity range;

determine a composite sensitivity value based on the determined sensitivity value and the retrieved prior sensitivity value; and

assign a successful calibration sensitivity value based on the retrieved prior sensitivity value when the variance is within the predetermined sensitivity range.

9. The apparatus of claim 8, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to:

determine a second sensitivity value associated with the analyte sensor after determining a composite sensitivity value;

determine whether a second variance between the second determined sensitivity value and the composite sensitivity value is within a predetermined sensitivity range; and

determine a second composite sensitivity value based on the second determined sensitivity value and the successful calibration sensitivity value when the second variance is within the predetermined sensitivity range.

10. The apparatus of claim 8, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to request a blood glucose value when the variance is outside the predetermined sensitivity range and a successful calibration sensitivity value has not been assigned.

11. The apparatus of claim 10 wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to prompt a user to input a blood glucose information.

12. The apparatus of claim 8 wherein the two sensitivity values are determined sequentially.

13. The apparatus of claim 8 wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to determine a weighted average of the determined sensitivity value and the retrieved sensitivity value.

14. The apparatus of claim 8, wherein the analyte sensor is a glucose sensor.

15. An analyte monitoring system, comprising:

a transcutaneously positionable analyte sensor for monitoring an analyte level;

an analyte monitoring device operatively coupled to the analyte sensor for receiving signals from the analyte sensor associated with the monitored analyte level; and

a data processing unit coupled to the analyte monitoring device, the data processing unit configured to;

determine a sensitivity value associated with an analyte sensor;

retrieve a prior sensitivity value associated with the analyte sensor;

determine whether a variance between the determined sensitivity value and the retrieved prior sensitivity value is within a predetermined sensitivity range;

determine a composite sensitivity value based on the determined sensitivity value and the retrieved prior sensitivity value; and

assign a successful calibration sensitivity value based on the retrieved prior sensitivity value when the variance is within the predetermined sensitivity range.

16. The system of claim 15, wherein the data processing unit is further configured to:

determine a second sensitivity value associated with the analyte sensor after determining a composite sensitivity value;

determine whether a second variance between the second determined sensitivity value and the composite sensitivity value is within a predetermined sensitivity range; and

determine a second composite sensitivity value based on the second determined sensitivity value and the successful calibration sensitivity value when the second variance is within the predetermined sensitivity range.

17. The system of claim 15, wherein the data processing unit is further configured to request a blood glucose value when the variance is outside the predetermined sensitivity range and a successful calibration sensitivity value has not been assigned.

18. The system of claim 15 wherein the data processing unit is further configured to prompt a user to input a blood glucose information.

19. The system of claim 15 wherein the processing unit is further configured to determine two sensitivity values sequentially.

20. The system of claim 15 wherein the processing unit is further configured to determine a weighted average of the determined sensitivity value and the retrieved sensitivity value.

21. The system of claim 15, wherein the analyte sensor is a glucose sensor and the monitored analyte level is a glucose level.