SYSTEM AND METHOD FOR REGENERATION OF A FLUID

• US 20100234795A1
• Filed: 08/16/2007
• Published: 09/16/2010
• Est. Priority Date: 08/16/2006
• Status: Active Grant

• Current Assignee: Triomed AB
• Original Assignee: Triomed AB
• Inventors: Wallenäs, Anders
• Granted Patent: US 8,282,828 B2
• Time in Patent Office: Days
• US Class Current: 604/29
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 1/3482 by filtrating the filtrate using another cross-flow filter, e.g. a membrane filter
• CPC Class Codes: B01D 61/025 Reverse osmosis; Hyperfiltration
• CPC Class Codes: B01D 61/027 Nanofiltration
• CPC Class Codes: B01D 61/145 Ultrafiltration
• CPC Class Codes: B01D 61/425 Electro-ultrafiltration
• CPC Class Codes: B01D 61/48 having one or more compartments filled with ion-exchange material , e.g. electrodeionisation
• CPC Class Codes: B01D 61/58 Multistep processes

Abstract

A method and a system for regenerating a body fluid, such as a peritoneal dialysis fluid. The body fluid is removed into an extracorporeal circuit comprising an electrofilter for removing charged ions from the body fluid, a nanofilter for removing large molecules, such as Dextran 40, and a reverse osmosis filter for concentrating the body fluid, for producing a synthetic urine to be discarded. The removed ions and large molecules are returned to the patient together with pure water from the reverse osmosis filter through an ultrafilter.

Claims

1. A system for regeneration of a body fluid, comprising:

a line for removing a body fluid from a patient;

a filter unit for retaining at least one component of the body fluid as a retentate fluid and for passing other components as a permeate fluid;

a reverse osmosis filter for concentrating the permeate fluid of the filter unit, for producing a synthetic urine to be discarded as a retentate fluid and essentially water as a permeate fluid;

a return line for returning the permeate fluid of the reverse osmosis filter and the retentate fluid of the filter unit to the patient; and

an electrofilter for removing charged ions from the body fluid and returning said ions to the patient.

3. The system according to claim 1, wherein said electrofilter is arranged before said reverse osmosis filter.

4. The system according to claim 3, wherein a second electrofilter is arranged after said reverse osmosis filter for removing charged ions from the synthetic urine.

5. The system according to claim 1, wherein the electrofilter comprises an anode and a cathode and ion exchange membranes, whereby a source of electric power is to be applied over the anode and cathode.

6. The system according to claim 5, wherein a first compartment is formed in the electrofilter between a cation membrane and an anion membrane, in which said body fluid is entered, and a second compartment is formed at the other side of the cation membrane and a third compartment is formed at the other side of the anion membrane, wherein a flushing fluid is arranged to pass through said second and said third compartments to flush out the ions separated by the membranes.

7. The system according to claim 6, wherein said flushing fluid is the retentate fluid of the filter unit or the permeate fluid of the reverse osmosis filter.

8. The system according to claim 1, further comprising an ultrafilter arranged in the return line to the patient.

9. The system according to claim 1, wherein the filter unit is a nanofilter having a membrane with a cut-off of about 500 Da.

2. (canceled)

10. A method for regenerating a body fluid, comprising:

removing a body fluid from a patient;

removing charged ions from the body fluid and returning said ions to the patient;

filtering said body fluid in a filter unit for retaining at least one component of the body fluid as a retentate fluid and for passing other components as a permeate fluid;

concentrating said permeate fluid of the filter unit using a reverse osmosis filter, for producing a synthetic urine to be discarded as a retentate fluid and essentially water as a permeate fluid;

returning the permeate fluid of the reverse osmosis filter and the retentate fluid of the filter unit to the patient.