SYSTEM AND METHOD FOR CONTROLLING RATE-ADAPTIVE PACING BASED ON A CARDIAC FORCE-FREQUENCY RELATION DETECTED BY AN IMPLANTABLE MEDICAL DEVICE
First Claim
1. A method for use with an implantable medical device for implant within a patient, wherein the device is equipped to perform rate-adaptive pacing, the method comprising:
- determining a force-frequency relationship for the heart of the patient, representative of the relationship between cardiac stimulation frequency and contractile force; and
controlling rate-adaptive pacing based on the force-frequency relationship.
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Accused Products
Abstract
Techniques are provided for use in controlling rate-adaptive pacing within implantable medical devices such as pacemakers or implantable cardioverter-defibrillators (ICDs). In one example, a force-frequency relationship is determined for the heart of the patient, which is representative of the relationship between cardiac stimulation frequency and myocardial contractile force. To this end, various parameters are detected for use as surrogates for contractile force, including selected systolic pressure parameters and cardiogenic impedance parameters. Rate-adaptive pacing is then controlled based on the detected force-frequency relationship to, for example, deactivate rate-adaptive pacing if the slope and/or abscissa of the force-frequency relationship indicates significant contractility dysfunction within the patient. In other examples, rather than deactivating rate-adaptive pacing, control parameters are adjusted to render the rate-adaptive pacing less aggressive. In still other examples, trends in the slope and/or abscissa of the force-frequency relationship are monitored to detect contractility dysfunction and/or heart failure and titrate medications accordingly.
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Citations
30 Claims
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1. A method for use with an implantable medical device for implant within a patient, wherein the device is equipped to perform rate-adaptive pacing, the method comprising:
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determining a force-frequency relationship for the heart of the patient, representative of the relationship between cardiac stimulation frequency and contractile force; and controlling rate-adaptive pacing based on the force-frequency relationship. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A system for use with an implantable medical device for implant within a patient, wherein the device is equipped to perform rate-adaptive pacing, the system comprising:
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a force-frequency relationship determination unit operative to determine a force-frequency relationship for the heart of the patient, representative of the relationship between cardiac stimulation frequency and contractile force; and a force-frequency-based rate-adaptive pacing controller operative to control rate-adaptive pacing based on the force-frequency relationship. - View Dependent Claims (26, 25, 27, 29)
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30. A system for use with an implantable medical device for implant within a patient, wherein the device is equipped to perform rate-adaptive pacing, the system comprising:
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means for determining a force-frequency relationship for the heart of the patient, representative of the relationship between cardiac stimulation frequency and contractile force; and means for controlling rate-adaptive pacing based on the force-frequency relationship.
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Specification