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LEAK-COMPENSATED PROPORTIONAL ASSIST VENTILATION

  • US 20100236553A1
  • Filed: 03/20/2009
  • Published: 09/23/2010
  • Est. Priority Date: 03/20/2009
  • Status: Active Grant
First Claim
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1. A method of compensating for leakage in a ventilation system during delivery of proportional assist ventilation to a patient comprising:

  • monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in the ventilation system;

    modeling leakage from the ventilation system as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system;

    estimating a leak-compensated instantaneous lung flow of gas inhaled or exhaled by the patient based on the one or more measurements, the first leakage component and second leakage component;

    using the leak-compensated lung flow and a predetermined respiratory mechanics model to estimate a leak-compensated lung compliance and a leak-compensated lung resistance; and

    calculating a pressure to be delivered to the patient based on the leak-compensated lung flow, the leak-compensated lung compliance and the leak-compensated lung resistance.

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