LEAK-COMPENSATED PRESSURE REGULATED VOLUME CONTROL VENTILATION
First Claim
1. A method of compensating for leakage in a ventilation system during delivery of pressure regulated volume control ventilation to a patient comprising:
- monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system;
modeling leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system;
estimating a leak-compensated delivered lung volume for at least one breath based on the one or more measurements, the first leakage component and the second leakage component;
using the leak-compensated delivered lung volume and a predetermined respiratory mechanics model to estimate a leak-compensated lung compliance; and
calculating a target pressure to be delivered to the patient for a subsequent breath based on a desired lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance.
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Accused Products
Abstract
This disclosure describes systems and methods for compensating for leakage when during delivery of gas to a patient from a medical ventilator in a pressure regulated volume control (PRVC) ventilation mode. The technology described herein includes systems and methods that compensate the delivery of PRVC ventilation for leakage in the patient circuit by using leak-compensated lung flows as well as respiratory mechanics (lung compliance and lung resistance) estimated in a manner that compensates for elastic and inelastic leaks from the ventilation system.
260 Citations
20 Claims
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1. A method of compensating for leakage in a ventilation system during delivery of pressure regulated volume control ventilation to a patient comprising:
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monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system; modeling leakage as a first leakage component through a first orifice of a fixed size and a second leakage component through a second orifice of a varying size, wherein the first and second leakage components are different functions of instantaneous pressure in the ventilation system; estimating a leak-compensated delivered lung volume for at least one breath based on the one or more measurements, the first leakage component and the second leakage component; using the leak-compensated delivered lung volume and a predetermined respiratory mechanics model to estimate a leak-compensated lung compliance; and calculating a target pressure to be delivered to the patient for a subsequent breath based on a desired lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method of compensating for leakage in a ventilation tubing system during delivery of gas from a medical ventilator to a patient comprising:
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measuring leakage from the ventilation tubing system during a first breath; calculating a leak-compensated delivered lung volume for the first breath based on the leakage; estimating a lung compliance of the patient based on the leak-compensated delivered lung volume and pressure measurements taken during the first breath; and delivering ventilation to the patient in a second breath at a pressure determined based on a desired delivered lung volume, the leak-compensated delivered lung volume and the leak-compensated lung compliance. - View Dependent Claims (8, 9, 10)
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11. A pressure support system comprising:
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a pressure generating system adapted to generate a flow of breathing gas; a ventilation tubing system including a patient interface device for connecting the pressure generating system to a patient; one or more sensors operatively coupled to the pressure generating system or the ventilation tubing system, each sensor capable of generating an output indicative of a pressure or flow of the breathing gas in the ventilation tubing system; a leak estimation module that identifies leakage in the ventilation tubing system; a delivered lung volume module that calculates a leak-compensated delivered lung volume for a first breath based on the leakage during the first breath and the flow of the breathing gas in the ventilation tubing system; a respiratory mechanics calculation module that generates a leak-compensated lung compliance based on the leak-compensated delivered lung volume and at least one output indicative of a pressure of the breathing gas during the first breath; and a pressure control module that causes the pressure generating system to deliver a second breath to the patient at a target pressure calculated based on the leak-compensated lung compliance and the leak-compensated delivered lung volume. - View Dependent Claims (12, 13, 14, 15, 16, 17)
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18. A controller for a medical ventilator comprising:
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a microprocessor; a module that calculates leak-compensated delivered lung volume and leak-compensated lung compliance based on instantaneous elastic leakage and instantaneous inelastic leakage of breathing gas from a ventilation system; and a pressure control module that provides pressure regulated volume control ventilation at a pressure determined based on the leak-compensated delivered lung volume and the leak-compensated lung compliance. - View Dependent Claims (19, 20)
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Specification