CONTROLLED ACTIVATION INGESTIBLE IDENTIFIER
First Claim
Patent Images
1. A pharmaceutical composition comprising:
- (a) a pharmaceutical active agent;
(b) a controlled activation identifier that emits a signal upon contact with a target site; and
(c) a pharmaceutically acceptable carrier.
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Abstract
Controlled activation identifiers for use in ingestible compositions, such as pharma-informatics enabled compositions, are provided. The identifiers include a controlled activation element that provides for activation of the identifier in response to the presence of a predetermined stimulus at a target site of interest. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.
147 Citations
51 Claims
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1. A pharmaceutical composition comprising:
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(a) a pharmaceutical active agent; (b) a controlled activation identifier that emits a signal upon contact with a target site; and (c) a pharmaceutically acceptable carrier.
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2-19. -19. (canceled)
- 20. A controlled activation ingestible identifier that emits a signal upon contact with target site fluid present at a target site.
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32. A system comprising:
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(a) a controlled activation ingestible identifier that emits a signal upon contact with target site fluid present at a target site; and (b) a receiver for detecting a signal produced by said identifier. - View Dependent Claims (33, 34)
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35. A method comprising:
administering to a subject a controlled activation ingestible identifier that emits a signal upon contact with target site fluid present at a target site.
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36-46. -46. (canceled)
- 47. A battery smaller than 10 mm3 comprising two materials with dissimilar electrochemical activities and a dried conductive medium precursor, wherein said battery is activated upon contact with a physiological fluid.
Specification